Trial · NCT02389036
Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients
NCT02389036, Phase 3, Completed, The George Institute
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients. Trials, record NCT02389036. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02389036
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients
- NCT number
- NCT02389036
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 20,010 participants, actual
- Lead sponsor
- The George Institute
- Conditions
- Critical Illness, Sepsis, Septic Shock, Ventilator Associated Pneumonia
- Interventions
- SDD Oral Paste, SDD Gastric Suspension, Intravenous Antibiotic
- First posted
- 2015-03-17
- Last updated
- 2023-08-14
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Hospital Mortality | Hospital discharge [up to Day 90 after randomization] | all-cause mortality at time of hospital discharge |
| Secondary | Total antibiotic usage | during ICU admission | Total antibiotic usage (as daily defined doses) during ICU admission in all ICU admissions. |
| Secondary | The incidence of antibiotic resistant organisms in cultures from blood or other sterile sites | during ICU admission | The incidence of antibiotic resistant organisms in cultures from blood or other sterile sites during ICU admission in all ICU admissions. |
| Secondary | The incidence of antibiotic-resistant organism in non-sterile clinical and surveillance specimens | during ICU admission | The incidence of antibiotic-resistant organism in non-sterile clinical and surveillance specimens during ICU admission in all ICU admissions |
| Secondary | The incidence of C. difficile infections | during ICU admission | The incidence of C. difficile infections during ICU admission in all ICU admissions |
| Secondary | Changes in antibiotic resistance rates between study epochs (pre-trial, interperiod gap and post-trial) within groups | Through out all study periods | Changes in ARO rates between time epochs (pre-trial, trial, inter-period gap and post-trial) within groups. With control group data to give the secular trend in ARO with time and SDD group data studying the effects of SDD withdrawal from practice in the year after SDD delivery |
| Secondary | Duration of mechanical ventilation | Time of enrolment to ICU discharge within index hospital admission,[up to Day 90 after randomization] | Duration that the patient is mechanically ventilated in the ICU |
| Secondary | ICU length of stay | From the time of enrolment to ICU discharge, [up to Day 90 after randomization] | The length of time a patient stays in the ICU |
| Secondary | Hospital length of stay | From time of enrolment to hospital discharge within the index hospital admission, [up to Day 90 after randomization] | The total hospital length of stay for patient |
| Secondary | ICU Mortality | ICU discharge [up to Day 90 after randomization] | mortality at time of ICU discharge |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers8
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02389036
GET https://conductscience.org/api/trials/v1/NCT02389036/registered