Trial · NCT02393300
Comparison of Topical Versus Intravenous Tranexamic Acid in TKA
NCT02393300, Phase 3, Completed, Shanghai Jiao Tong University School of Medicine
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparison of Topical Versus Intravenous Tranexamic Acid in TKA. Trials, record NCT02393300. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02393300
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparison of Topical Versus Intravenous Tranexamic Acid in TKA
- NCT number
- NCT02393300
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 174 participants, actual
- Lead sponsor
- Shanghai Jiao Tong University School of Medicine
- Conditions
- Total Blood Loss
- Interventions
- normal saline, Tranexamic Acid, Tranexamic Acid
- First posted
- 2015-03-19
- Last updated
- 2018-04-04
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Total Blood Loss（TBL） | calculated by an equation at the fifth postoperative day | Total Blood Loss（TBL） was calculated with equations described by Gross et al. |
| Secondary | Transfusion rates | from the day of surgery to the day of discharge,an expected average of 7 days | Include The number of units of perioperative blood transfusions, both intraoperative and postoperative, over the course of the patient's hospital stay |
| Other | Venous thromboembolic event (symptomatic deep vein thrombosis or pulmonary | twelve weeks after surgery | Clinically proven symptomatic deep vein thrombosis (DVT) or pulmonary embolism |
| Other | other thromboembolic event | twelve weeks after surgery | Clinically proven Acute Myocardial Infarction、acute kidney infarction or cerebral infarction |
| Other | drainage output | it will be recorded at the first day and the second day after surgery | |
| Other | human serum albumin usage | from the day of surgery to the day of discharge,an expected average of 7 days | the investigators will record the dosage of the human blood albumin used in each patient. |
| Other | American Society of Anesthesiologists Physical Status Classification (ASA class) | at the day of surgery | |
| Other | Disseminated Intravascular Coagulation（DIC） | at any day before surgery and the first the fifth day after surgery |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02393300
GET https://conductscience.org/api/trials/v1/NCT02393300/registered