Trial · NCT02419573
Pragmatic Airway Resuscitation Trial
NCT02419573, Not applicable, Completed, University of Alabama at Birmingham; results first posted 2018-12-12
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Pragmatic Airway Resuscitation Trial. Trials, record NCT02419573. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02419573
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Pragmatic Airway Resuscitation Trial
- NCT number
- NCT02419573
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 3,004 participants, actual
- Lead sponsor
- University of Alabama at Birmingham
- Conditions
- Cardiac Arrest
- Interventions
- Endotracheal Intubation, Laryngeal Tube (King)
- First posted
- 2015-04-17
- Last updated
- 2019-01-14
- Results first posted
- 2018-12-12
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Patients Alive at 72 Hours After Episode. | 72 hours | Number of patient alive at 72 hours after episode. |
| Secondary | Return of Spontaneous Circulation (ROSC) | Patients will be followed from the time of the CA until death or ROSC whichever occurs first. The time frame for this secondary outcome may vary from minutes to hours, but is not expected to last longer than 12 hours. | Presence of palpable pulses on Emergency Department arrival. Patients pronounced dead in the field coded as ROSC=\[none\]. |
| Secondary | Number of Patients Alive at Hospital Discharge | From enrollment through end of hospital course. Maximum time interval not specified. Maximum time interval observed in study was 138 days. | Number of patients alive at time hospital discharge. |
| Secondary | Number of Patients With Favorable Neurologic Status on Hospital Discharge | From enrollment through end of hospital course. | Number of patients with favorable neurologic status, defined as Modified Rankin Scale (MRS) \<=3. MRS values for neurologic outcome include: 0 - No symptoms. 1. \- No significant disability. Able to carry out all usual activities, despite some symptoms. 2. \- Slight disability. Able to look after own affairs without assistance, but unable to carry out all previous activities. 3. \- Moderate disability. Requires some help, but able to walk unassisted. 4. \- Moderately severe disability. Unable to attend to own bodily needs without assistance, and unable to walk unassisted. 5. \- Severe disability. Requires constant nursing care and attention, bedridden, incontinent. 6. \- Dead. |
Source ClinicalTrials.gov
Outcomes4
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number of Patients Alive at 72 Hours After Episode. | 72 hours | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Return of Spontaneous Circulation (ROSC) | Patients will be followed from the time of the CA until death or ROSC whichever occurs first. The time frame for this secondary outcome may vary from minutes to hours, but is not expected to last longer than 12 hours. | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Number of Patients Alive at Hospital Discharge | From enrollment through end of hospital course. Maximum time interval not specified. Maximum time interval observed in study was 138 days. | Outcome for 1 patient in LT group not known. | Participants | COUNT_OF_PARTICIPANTS |
| SECONDARY | Number of Patients With Favorable Neurologic Status on Hospital Discharge | From enrollment through end of hospital course. | Neurologic status not known for 4 patients in the ETI group and 5 patients in LT group. | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group8
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Number of Patients Alive at 72 Hours After Episode. | Endotracheal Intubation | 230 | Participants | ||
| Number of Patients Alive at 72 Hours After Episode. | Laryngeal Tube (King) | 275 | Participants | ||
| Return of Spontaneous Circulation (ROSC) | Endotracheal Intubation | 361 | Participants | ||
| Return of Spontaneous Circulation (ROSC) | Laryngeal Tube (King) | 420 | Participants | ||
| Number of Patients Alive at Hospital Discharge | Endotracheal Intubation | 121 | Participants | ||
| Number of Patients Alive at Hospital Discharge | Laryngeal Tube (King) | 163 | Participants | ||
| Number of Patients With Favorable Neurologic Status on Hospital Discharge | Endotracheal Intubation | 75 | Participants | ||
| Number of Patients With Favorable Neurologic Status on Hospital Discharge | Laryngeal Tube (King) | 107 | Participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Endotracheal Intubation | 1,499 | |
| Overall Study | STARTED | Laryngeal Tube (King) | 1,505 | |
| Overall Study | COMPLETED | Endotracheal Intubation | 1,495 | |
| Overall Study | COMPLETED | Laryngeal Tube (King) | 1,505 | |
| Overall Study | NOT COMPLETED | Endotracheal Intubation | 4 | |
| Overall Study | NOT COMPLETED | Laryngeal Tube (King) | 0 |
Source ClinicalTrials.gov
Adverse events10
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Multiple (>=3) attempts to insert the assigned airway. | Injury, poisoning and procedural complications | Endotracheal Intubation | 245 | 1,299 | 245 |
| other | Multiple (>=3) attempts to insert the assigned airway. | Injury, poisoning and procedural complications | Laryngeal Tube (King) | 61 | 1,353 | 61 |
| other | Unsuccessful insertion of assigned airway. | Injury, poisoning and procedural complications | Endotracheal Intubation | 573 | 1,299 | 573 |
| other | Unsuccessful insertion of assigned airway. | Injury, poisoning and procedural complications | Laryngeal Tube (King) | 159 | 1,353 | 159 |
| other | Pneumothorax | Respiratory, thoracic and mediastinal disorders | Endotracheal Intubation | 30 | 426 | 30 |
| other | Pneumothorax | Respiratory, thoracic and mediastinal disorders | Laryngeal Tube (King) | 17 | 485 | 17 |
| other | Rib Fracture | Respiratory, thoracic and mediastinal disorders | Endotracheal Intubation | 30 | 426 | 30 |
| other | Rib Fracture | Respiratory, thoracic and mediastinal disorders | Laryngeal Tube (King) | 16 | 85 | 16 |
| other | Pneumonia or Aspiration Pneumonitis | Respiratory, thoracic and mediastinal disorders | Endotracheal Intubation | 89 | 398 | 89 |
| other | Pneumonia or Aspiration Pneumonitis | Respiratory, thoracic and mediastinal disorders | Laryngeal Tube (King) | 120 | 460 | 120 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Endotracheal Intubation | 1,265 | 1,495 |
| Total, all-cause mortality | Laryngeal Tube (King) | 1,230 | 1,505 |
| Total, other adverse events | Endotracheal Intubation | 582 | 1,495 |
| Total, other adverse events | Laryngeal Tube (King) | 173 | 1,505 |
| Total, serious adverse events | Endotracheal Intubation | 0 | 1,495 |
| Total, serious adverse events | Laryngeal Tube (King) | 0 | 1,505 |
Source ClinicalTrials.gov
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants2
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|---|---|---|---|---|---|
| U01HL077863 | Resuscitation Outcomes Consortium (ROC) Data Coordinating Center | MAY, SUSANNE | UNIVERSITY OF WASHINGTON | NATIONAL HEART, LUNG, AND BLOOD INSTITUTE | 2004 to 2015 | NIH RePORTER |
| UH2HL125163 | Pragmatic Trial of Airway Management in Out-of-Hospital Cardiac Arrest | WANG, HENRY E. | UNIVERSITY OF ALABAMA AT BIRMINGHAM | NATIONAL HEART, LUNG, AND BLOOD INSTITUTE | 2014 | NIH RePORTER |
Trial comparisons6
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Endotracheal Intubation vs Laryngeal Tube (King): Number of Patients Alive at Hospital Discharge | Trial comparisons |
| Endotracheal Intubation vs Laryngeal Tube (King): Return of Spontaneous Circulation (ROSC) | Trial comparisons |
| Endotracheal Intubation vs Laryngeal Tube (King): Number of Patients Alive at 72 Hours After Episode. | Trial comparisons |
| Endotracheal Intubation vs Laryngeal Tube (King): Number of Patients With Favorable Neurologic Status on Hospital Discharge | Trial comparisons |
| Endotracheal Intubation vs Laryngeal Tube (King): deaths from any cause | Trial comparisons |
| Endotracheal Intubation vs Laryngeal Tube (King): serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02419573
GET https://conductscience.org/api/trials/v1/NCT02419573/registered