Trial · NCT02453841
Prospective Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption
NCT02453841, Not applicable, Completed, Richard Cartabuke; results first posted 2018-09-18
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Prospective Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption. Trials, record NCT02453841. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02453841
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Prospective Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption
- NCT number
- NCT02453841
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 30 participants, actual
- Lead sponsor
- Richard Cartabuke
- Conditions
- Adenoidectomy, Functional Endoscopic Sinus Surgery (FESS), Turbinate Surgery
- Interventions
- Oxymetazoline
- First posted
- 2015-05-27
- Last updated
- 2018-09-18
- Results first posted
- 2018-09-18
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Blood Pressure Following Oxymetazoline Administration | 5 - 150 mins. after administration | Blood pressure was recorded at 5 minute intervals until discharge from the post-anesthesia care unit (PACU) or the final blood draw (150 mins. after administration), whichever came first. |
| Primary | Heart Rate Following Oxymetazoline Administration. | 5 - 150 mins. after administration | Heart rate was recorded at 5 minute intervals until discharge from the post-anesthesia care unit (PACU) or the final blood draw (150 mins. after administration), whichever came first. |
| Secondary | Ease of Hemostasis | intraoperative | A six point scale (very easy, easy, usual, some effort, difficult, extremely difficult) completed by the surgeon at the end of surgery. |
| Secondary | Amount of Bleeding | intraoperative | A four point scale (none, minimal, moderate/diffuse ooze, severe/brisk) completed by the surgeon after removal of the oxymetazoline soaked pledgets. |
Source ClinicalTrials.gov
Outcomes4
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Blood Pressure Following Oxymetazoline Administration | 5 - 150 mins. after administration | mmHg | MEAN | |
| PRIMARY | Heart Rate Following Oxymetazoline Administration. | 5 - 150 mins. after administration | beats per minute | MEAN | |
| SECONDARY | Ease of Hemostasis | intraoperative | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Amount of Bleeding | intraoperative | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group10
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Blood Pressure Following Oxymetazoline Administration | Children Undergoing ENT Surgery | Systolic blood pressure | 102 | Standard Deviation 16 | mmHg |
| Blood Pressure Following Oxymetazoline Administration | Children Undergoing ENT Surgery | Diastolic blood pressure | 53 | Standard Deviation 17 | mmHg |
| Blood Pressure Following Oxymetazoline Administration | Children Undergoing ENT Surgery | Mean arterial pressure | 65 | Standard Deviation 15 | mmHg |
| Heart Rate Following Oxymetazoline Administration. | Children Undergoing ENT Surgery | 98 | Standard Deviation 22 | beats per minute | |
| Ease of Hemostasis | Children Undergoing ENT Surgery | Very Easy | 10 | Participants | |
| Ease of Hemostasis | Children Undergoing ENT Surgery | Easy | 9 | Participants | |
| Ease of Hemostasis | Children Undergoing ENT Surgery | Usual | 8 | Participants | |
| Amount of Bleeding | Children Undergoing ENT Surgery | None | 11 | Participants | |
| Amount of Bleeding | Children Undergoing ENT Surgery | Minimal | 11 | Participants | |
| Amount of Bleeding | Children Undergoing ENT Surgery | Moderate | 5 | Participants |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Children Undergoing ENT Surgery | 30 | |
| Overall Study | COMPLETED | Children Undergoing ENT Surgery | 27 | |
| Overall Study | NOT COMPLETED | Children Undergoing ENT Surgery | 3 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Children Undergoing ENT Surgery | 0 | 30 |
| Total, other adverse events | Children Undergoing ENT Surgery | 0 | 30 |
| Total, serious adverse events | Children Undergoing ENT Surgery | 0 | 30 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02453841
GET https://conductscience.org/api/trials/v1/NCT02453841/registered