Trial · NCT02465645
To Compare the Efficacy and Safety of Carvedilol With or Without Simvastatin in Patients With Portal Hypertension and Esophageal Varices.
NCT02465645, Not applicable, Completed, Institute of Liver and Biliary Sciences, India
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. To Compare the Efficacy and Safety of Carvedilol With or Without Simvastatin in Patients With Portal Hypertension and Esophageal Varices. Trials, record NCT02465645. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02465645
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- To Compare the Efficacy and Safety of Carvedilol With or Without Simvastatin in Patients With Portal Hypertension and Esophageal Varices.
- NCT number
- NCT02465645
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 220 participants, actual
- Lead sponsor
- Institute of Liver and Biliary Sciences, India
- Conditions
- Cirrhosis With Esophageal Varices
- Interventions
- Carvedilol, Carvedilol + Simvastatin
- First posted
- 2015-06-08
- Last updated
- 2018-05-11
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Total number of patients who will be Responders. | 3 Months | Responders (Absolute value of HVPG\<12 mm Hg or HVPG≥20% reduction) |
| Secondary | Total number of patients develop esophageal variceal bleed | 3 months | |
| Secondary | Total number of patients develop PHG (Portal Hypertensive Gastropathy). | 3 months | |
| Secondary | Total number of patients develop GAVE (Gastric Antral Vascular Ectasia). | 3 months | |
| Secondary | Total number of patients develop Gastric Varices. | 3 months | |
| Secondary | Total number of patients develop adverse Events of the study drug | 3 months | |
| Secondary | Improvement in the CTP (Child-Turcotte-Pugh score) score. | 3 months | |
| Secondary | Improvement in the MELD (Model for End Stage liver Disease) score. | 3 months |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 32079861 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02465645
GET https://conductscience.org/api/trials/v1/NCT02465645/registered