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Trial · NCT02474355

Results by group14

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Overall Survival (OS)Osimertinib22.895% Confidence Interval 21.6 to 23.8Months
Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)OsimertinibAE of special interest (AESI) or SAE923Participants
Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)OsimertinibAESI or SAE a causally related to Osimertinib338Participants
Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)OsimertinibAE leading to dose modification414Participants
Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)OsimertinibAE leading to discontinuation191Participants
Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)OsimertinibAESI113Participants
Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)OsimertinibAESI causally related to Osimertinib89Participants
Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)OsimertinibSAE657Participants
Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)OsimertinibSAE causally related to Osimertinib95Participants
Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)OsimertinibAE leading to death152Participants
Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)OsimertinibAE leading to death causally related to Osimertinib19Participants
Progression Free SurvivalOsimertinib11.195% Confidence Interval 11.0 to 12.0Months
Time to Treatment Discontinuation (TTD)Osimertinib13.595% Confidence Interval 12.6 to 13.9Months
Response Rate (RR)Osimertinib57.395% Confidence Interval 55.5 to 59.2Percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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