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Trial · NCT02477696

Results by group126

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Progression-free Survival (PFS) Based on Independent Review Committee (IRC) AssessmentAcalabrutinib38.495% Confidence Interval 33.0 to 38.6Months
Progression-free Survival (PFS) Based on Independent Review Committee (IRC) AssessmentIbrutinib38.495% Confidence Interval 33.0 to 41.6Months
Number of Participants With Treatment-emergent Infections Grade >= 3Acalabrutinib98Participants
Number of Participants With Treatment-emergent Infections Grade >= 3Ibrutinib101Participants
Number of Participants With Treatment-emergent Richter's TransformationAcalabrutinib13Participants
Number of Participants With Treatment-emergent Richter's TransformationIbrutinib14Participants
Number of Participants With Treatment-emergent Atrial FibrillationAcalabrutinib32Participants
Number of Participants With Treatment-emergent Atrial FibrillationIbrutinib49Participants
Overall Survival (OS)AcalabrutinibNA95% Confidence Interval NA to NAMonths
Overall Survival (OS)IbrutinibNA95% Confidence Interval 65.0 to NAMonths
Number of Participants With Treatment-emergent Adverse Events (TEAEs) and Treatment-emergent Serious Adverse Events (TESAEs)AcalabrutinibAny TEAEs262Participants
Number of Participants With Treatment-emergent Adverse Events (TEAEs) and Treatment-emergent Serious Adverse Events (TESAEs)IbrutinibAny TEAEs259Participants
Number of Participants With Treatment-emergent Adverse Events (TEAEs) and Treatment-emergent Serious Adverse Events (TESAEs)AcalabrutinibAny TESAEs161Participants
Number of Participants With Treatment-emergent Adverse Events (TEAEs) and Treatment-emergent Serious Adverse Events (TESAEs)IbrutinibAny TESAEs177Participants
Number of Participants With Treatment-emergent Laboratory AbnormalitiesAcalabrutinibAbsolute neutrophil count (decreased)124Participants
Number of Participants With Treatment-emergent Laboratory AbnormalitiesIbrutinibAbsolute neutrophil count (decreased)135Participants
Number of Participants With Treatment-emergent Laboratory AbnormalitiesAcalabrutinibHaemoglobin (decreased)139Participants
Number of Participants With Treatment-emergent Laboratory AbnormalitiesIbrutinibHaemoglobin (decreased)131Participants
Number of Participants With Treatment-emergent Laboratory AbnormalitiesAcalabrutinibPlatelets (decreased)119Participants
Number of Participants With Treatment-emergent Laboratory AbnormalitiesIbrutinibPlatelets (decreased)116Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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