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Trial · NCT02480335

Registered outcomes32

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
SecondarySkin Autofluorescence3 and 12 monthsassessed with the AGE Reader
SecondaryNumber of new digital ulcers3 and 12 monthsNumber
SecondaryTime to healing of digital ulcers3 and 12 monthsIn days
SecondaryUrine albumin/creatinine ratio (ACR)3 and 12 monthsMeasured in two separate morning samples of urine
SecondaryPlasma N-terminal of the prohormone brain natriuretic peptide (NT-proBNP)3 and 12 monthsassessed using a routine assay
SecondarySerum levels of matrix metalloproteinase 33 and 12 monthsmeasured according to the manufacturer's instructions
SecondarySerum levels of matrix metalloproteinases 93 and 12 monthsdetermined using in-house enzyme-linked immunosorbent assays (ELISAs)
SecondarySerum levels of tissue inhibitors of metalloproteinases (TIMP)3 and 12 monthsdetermined using in-house enzyme-linked immunosorbent assays
SecondaryBlood pressure of the brachial artery3 and 12 monthssystolic/diastolic in mmHg
SecondaryModified Rodnan Skin Score (mRSS)3 and 12 months17 body areas are examined by clinical palpation and scored based on examiner judgement of skin thickness on a 4-point ordinal scale.
SecondaryScleroderma Health Assessment Questionnaire (SHAQ)3 and 12 monthsquestionnaire
SecondaryShort Form (36)3 and 12 monthsquestionnaire

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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