Trial · NCT02484703
A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age
NCT02484703, Phase 2, Terminated, Hoffmann-La Roche
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age. Trials, record NCT02484703. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02484703
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age
- NCT number
- NCT02484703
- Status
- Terminated
- Phases
- Phase 2
- Enrollment
- 45 participants, actual
- Lead sponsor
- Hoffmann-La Roche
- Conditions
- Down Syndrome
- Interventions
- Placebo, RO5186582
- First posted
- 2015-06-30
- Last updated
- 2017-07-06
Source ClinicalTrials.gov
Registered outcomes23
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percentage of Participants With Adverse Events (AEs) | Baseline up to Week 6 | |
| Primary | Percentage of Participants With Epileptiform Abnormalities as Assessed Using Electroencephalogram (EEG) Analysis | Baseline up to Week 6 | |
| Primary | Percentage of Participants by Suicidality Classification as Assessed Using an Adapted Form of the Columbia Classification Algorithm for Suicide Assessment (C-CASA) | Baseline up to Week 6 | |
| Primary | Anxiety, Depression, and Mood Scale (ADAMS) Score | Baseline up to Week 6 | |
| Primary | Hyperactivity and Impulsivity as Assessed by the Short Version of Conners Third Edition Parent Short-Form (Conners-3) Score | Baseline up to Week 6 | |
| Primary | Sleep Disturbances as Assessed by the Children's Sleep Habits Questionnaire (CSHQ) Score | Baseline up to Week 6 | |
| Primary | Gamma Power at Posterior Electrodes as Assessed Using EEG Analysis | Baseline up to Week 6 | |
| Primary | Theta Power at Posterior Electrodes as Assessed Using EEG Analysis | Baseline up to Week 6 | |
| Primary | Cognition as Assessed by the Children's Memory Scale (CMS) Subtests Score | Baseline up to Week 6 | |
| Secondary | Percentage of Participants With AEs | Baseline up to Week 26 |
1 to 10 of 23Source ClinicalTrials.gov
See all 23 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02484703
GET https://conductscience.org/api/trials/v1/NCT02484703/registered?page=2