Trial · NCT02492841
Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
NCT02492841, Phase 2, Phase 3, Completed, Universidad de los Andes, Chile; results first posted 2017-08-14
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth. Trials, record NCT02492841. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02492841
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
- NCT number
- NCT02492841
- Status
- Completed
- Phases
- Phase 2, Phase 3
- Enrollment
- 169 participants, actual
- Lead sponsor
- Universidad de los Andes, Chile
- Conditions
- Caries, Dental Pulp Exposure
- Interventions
- Mineral trioxide aggregate, Calcium hydroxide, Biodentine
- First posted
- 2015-07-09
- Last updated
- 2024-05-30
- Results first posted
- 2017-08-14
- Limitations and caveats
The small sample due to inclusion criteria. Lack of collaboration from the primary health providers. And the fact that the oral health seems not to be a priority and people only come when it hurts and it is too late for prevention.
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Parameters Evaluated After Treatment | 3 months, 6 moths and 12 months | vitality test with electric device cold and hot test radiographic evaluation |
| Secondary | Number of Participants With Adverse Effects | 1 week, 3 and 6 months | Name any adverse effects caused by treatment. |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Parameters Evaluated After Treatment | 3 months, 6 moths and 12 months | Intent a preventive treatment against cavities to avoid endodoncies with different treatments and see which one is more effective after 12 months follow up. | Participants | COUNT_OF_PARTICIPANTS |
| SECONDARY | Number of Participants With Adverse Effects | 1 week, 3 and 6 months | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group9
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Parameters Evaluated After Treatment | Mineral Trioxide Aggregate (MTA) | Succesfull treatment | 19 | Participants | |
| Parameters Evaluated After Treatment | Calcium Hydroxide | Succesfull treatment | 19 | Participants | |
| Parameters Evaluated After Treatment | Biodentine | Succesfull treatment | 25 | Participants | |
| Parameters Evaluated After Treatment | Mineral Trioxide Aggregate (MTA) | Need other treatment | 3 | Participants | |
| Parameters Evaluated After Treatment | Calcium Hydroxide | Need other treatment | 3 | Participants | |
| Parameters Evaluated After Treatment | Biodentine | Need other treatment | 0 | Participants | |
| Number of Participants With Adverse Effects | Mineral Trioxide Aggregate (MTA) | 0 | Participants | ||
| Number of Participants With Adverse Effects | Calcium Hydroxide | 0 | Participants | ||
| Number of Participants With Adverse Effects | Biodentine | 0 | Participants |
Source ClinicalTrials.gov
Participant flow9
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Mineral Trioxide Aggregate (MTA) | 56 | |
| Overall Study | STARTED | Calcium Hydroxide | 53 | |
| Overall Study | STARTED | Biodentine | 60 | |
| Overall Study | COMPLETED | Mineral Trioxide Aggregate (MTA) | 22 | |
| Overall Study | COMPLETED | Calcium Hydroxide | 22 | |
| Overall Study | COMPLETED | Biodentine | 25 | |
| Overall Study | NOT COMPLETED | Mineral Trioxide Aggregate (MTA) | 34 | |
| Overall Study | NOT COMPLETED | Calcium Hydroxide | 31 | |
| Overall Study | NOT COMPLETED | Biodentine | 35 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals9
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Mineral Trioxide Aggregate (MTA) | 0 | 22 |
| Total, all-cause mortality | Calcium Hydroxide | 0 | 22 |
| Total, all-cause mortality | Biodentine | 0 | 25 |
| Total, other adverse events | Mineral Trioxide Aggregate (MTA) | 0 | 22 |
| Total, other adverse events | Calcium Hydroxide | 0 | 22 |
| Total, other adverse events | Biodentine | 0 | 25 |
| Total, serious adverse events | Mineral Trioxide Aggregate (MTA) | 0 | 22 |
| Total, serious adverse events | Calcium Hydroxide | 0 | 22 |
| Total, serious adverse events | Biodentine | 0 | 25 |
Source ClinicalTrials.gov
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02492841
GET https://conductscience.org/api/trials/v1/NCT02492841/registered