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Trial · NCT02497287

Results by group47

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Participants With Treatment-Emergent Adverse Events (TEAEs)Intranasal Esketamine + Oral Antidepressant90.1Percentage of participants
Percentage of Participants With Cystitis, Urinary Tract Infections, Renal and Urinary Tract Symptoms, Renal and Urinary DisordersIntranasal Esketamine + Oral AntidepressantCystitis0.6Percentage of participants
Percentage of Participants With Cystitis, Urinary Tract Infections, Renal and Urinary Tract Symptoms, Renal and Urinary DisordersIntranasal Esketamine + Oral AntidepressantUrinary tract infections8.1Percentage of participants
Percentage of Participants With Cystitis, Urinary Tract Infections, Renal and Urinary Tract Symptoms, Renal and Urinary DisordersIntranasal Esketamine + Oral AntidepressantRenal and urinary disorders10.5Percentage of participants
Percentage of Participants With Cystitis, Urinary Tract Infections, Renal and Urinary Tract Symptoms, Renal and Urinary DisordersIntranasal Esketamine + Oral AntidepressantRenal and urinary tract symptoms17.0Percentage of participants
Change From Baseline in Cognitive Test Battery: Detection Test (DET) ScoreIntranasal Esketamine + Oral Antidepressant-0.0028Standard Deviation 0.12744log10 msec
Change From Baseline in Cognitive Test Battery: Identification Test (IDN) ScoreIntranasal Esketamine + Oral Antidepressant-0.0083Standard Deviation 0.09656log10 msec
Change From Baseline in Cognitive Test Battery: One Card Learning Test (OCL) ScoreIntranasal Esketamine + Oral Antidepressant0.0502Standard Deviation 0.13149Arcsine ([sqrt] of proportion of [CR])
Change From Baseline in Cognitive Test Battery: One Back Test (ONB) ScoreIntranasal Esketamine + Oral Antidepressant0.0177Standard Deviation 0.10026log10 msec
Change From Baseline in Cognitive Test Battery: Groton Maze Learning Test (GMLT) ScoreIntranasal Esketamine + Oral Antidepressant6.9Standard Deviation 25.36Number of Errors
Change From Baseline in Hopkins Verbal Learning Test-Revised (HVLT-R) Score: Total RecallIntranasal Esketamine + Oral Antidepressant2.8Standard Deviation 4.74Number correct
Change From Baseline in Hopkins Verbal Learning Test-Revised (HVLT-R) Score: Delayed RecallIntranasal Esketamine + Oral Antidepressant0.8Standard Deviation 2.31Number correct
Change From Baseline in Hopkins Verbal Learning Test-Revised (HVLT-R) Score: Number of Words RecalledIntranasal Esketamine + Oral Antidepressant0.3Standard Deviation 2.83Number of words recalled
Change From Baseline in Hopkins Verbal Learning Test-Revised (HVLT-R) Score: Recognition Discrimination IndexIntranasal Esketamine + Oral Antidepressant0.5Standard Deviation 3.16Number of words
Change From Baseline to Endpoint in Montgomery Asberg Depression Rating Scale (MADRS) Total Score During Induction (IND) PhaseIntranasal Esketamine + Oral Antidepressant-16.4Standard Deviation 8.76Units on a Scale
Change From Baseline to Endpoint in MADRS Total Score During Optimization/Maintenance (OP/MA) PhaseIntranasal Esketamine + Oral Antidepressant0.3Standard Deviation 8.12Units on a Scale
Change From Baseline to Endpoint in Patient Health Questionnaire - 9 (PHQ-9) Total Score During IND PhaseIntranasal Esketamine + Oral Antidepressant-8.9Standard Deviation 6.67Unit on a Scale
Change From Baseline to Endpoint in PHQ-9 Total Score During OP/MA PhaseIntranasal Esketamine + Oral Antidepressant-0.2Standard Deviation 5.65Units on a Scale
Change From Baseline to Endpoint in Clinical Global Impression of Severity (CGI-S) Scale Score During IND PhaseIntranasal Esketamine + Oral Antidepressant-2.0Full Range -6 to 2Units on a Scale
Change From Baseline to Endpoint in CGI-S Scale Score During OP/MA PhaseIntranasal Esketamine + Oral Antidepressant0.0Full Range -3 to 4Units on a Scale

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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