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Trial · NCT02523976

Dasatinib Combined With Chemotherapy in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia

NCT02523976, Phase 2, Completed, Institute of Hematology & Blood Diseases Hospital, China

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Dasatinib Combined With Chemotherapy in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia. Trials, record NCT02523976. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02523976

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Dasatinib Combined With Chemotherapy in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia
NCT number
NCT02523976
Status
Completed
Phases
Phase 2
Enrollment
30 participants, actual
Lead sponsor
Institute of Hematology & Blood Diseases Hospital, China
Conditions
Acute,Leukemia, Lymphoid
Interventions
Dasatinib, prednisone, cyclophosphamide, daunorubicin, vincristine, cytarabine, mercaptopurine, methotrexate, dexamethasone, mitoxantrone, etoposide, allogeneic hematopoietic stem cell transplantation, autologous hematopoietic stem cell transplantation
First posted
2015-08-14
Last updated
2026-02-11

Source ClinicalTrials.gov

Registered outcomes8

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryOverall survival (OS)From date of diagnosis until the date of death from any cause, assessed up to 60 months.
SecondaryDisease-free survival (DFS)From the date of complete remission(CR) until the date of documented relapse,assessed up to 60 months.
SecondaryThe complete remission (CR) rateParticipants will be followed for the duration of the treatment, an expected average of 6 months.
SecondaryThe molecular CR rateParticipants will be followed for the duration of the treatment, an expected average of 24 months.
SecondaryThe plasma level of dasatinib in the regimenUp to 3 months.
SecondaryThe Cerebrospinal fluid level of dasatinib in the regimenUp to 6 months.
SecondaryNumber of adverse event of combined treatmentParticipants will be followed for the duration of the treatment, an expected average of 24 months.
SecondaryGrade of adverse event of combined treatmentParticipants will be followed for the duration of the treatment, an expected average of 24 months.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers2

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
33858040DERIVEDPubMed
34120773DERIVEDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT02523976

GET https://conductscience.org/api/trials/v1/NCT02523976/registered