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Trial · NCT02536846

Outcomes33

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured as
PRIMARYChange in Brain Nicotinamide Adenine Dinucleotide Metabolites NAD+/NADHBaseline and after 15 days medication periodratioMEAN
PRIMARYChange in Brain Phosphocreatine (PCr)Baseline and after 15 days medication periodratioMEAN
PRIMARYChange in Brain Creatine Kinase (CK) Forward Reaction RateBaseline and after 15 days medication periods-1MEAN
PRIMARYChange in Brain Parenchymal pHbaseline and after 15 days medication periodpHMEAN
SECONDARYChange in Volumes of the Frontal, Parietal and Temporal Lobe Regionsbaseline and after 15 day medication periodcubic mmMEAN
SECONDARYChange in Surface Area of the Frontal, Parietal and Temporal Regionsbaseline and after 15 days medication periodmm^2MEAN
SECONDARYChange in fMRI Resting State Functional Connectivitybaseline and after 15 days medication periodNumber of voxels that showed significant change in connectivity following administration of olanzapine.VoxelsNUMBER
SECONDARYChange in GABA Concentrationbaseline and after 15 days medication periodmmolMEAN
SECONDARYChange in Fractional Anisotropy (FA) Measured by Diffusion Tensor Imaging (DTI)baseline and after 15 days medication periodUnits on a scaleMEAN
SECONDARYChange in Glutamate Metabolite Concentrationbaseline and after 15 days medication periodmillimolesMEAN
SECONDARYChange in MATRICS Cognitive Consensus Battery (MCCB) Total Composite Scorebaseline and after 15 days medication periodScore on a scaleMEAN
OTHER_PRE_SPECIFIEDChange in Montgomery-Asberg Depression Rating Scale (MADRS) Scorebaseline and after 15 days medication periodscore on a scaleMEAN
OTHER_PRE_SPECIFIEDChange in Beck Depression Inventory (BDI) Scorebaseline and after 15 days medication periodscore on a scaleMEAN
OTHER_PRE_SPECIFIEDChange in Young Mania Rating Scale (YMRS) Scorebaseline and after 15 days medication periodscore on a scaleMEAN
OTHER_PRE_SPECIFIEDChange in Beck Anxiety Inventory (BAI) Scorebaseline and after 15 days medication periodscore on a scaleMEAN
OTHER_PRE_SPECIFIEDChange in The Columbia Suicide Severity Rating Scale Scorebaseline and 2, 5, 10, 15 days during medication periodData for this measure was collected for 10 participants.score on a scaleMEAN
OTHER_PRE_SPECIFIEDChange in Pittsburgh Sleep Quality Index Scorebaseline and after 15 days medication periodscore on a scaleMEAN
OTHER_PRE_SPECIFIEDChange in LUNSERS (Liverpool University Neuroleptic Side Effect Rating Scale) Scorebaseline and 2, 5, 10 and 15 days (or final assessment) during medication periodData for this measure was collected for 10 participants.score on a scaleMEAN
OTHER_PRE_SPECIFIEDChange in Body Weightbaseline and 2, 5, 10 and 15 days (or final assessment) during medication periodData for this measure was collected for 10 participantskgMEAN
OTHER_PRE_SPECIFIEDChange in Hip Circumferencebaseline and 2, 5, 10 and 15 days (or final assessment) during medication periodData for this measure was collected for 10 participants.cmMEAN

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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