Synergistic Effects of Aerobic Exercise and Cognitive Training on Cognition in Stroke Patients With Cognitive Decline
NCT02550990, Not applicable, Unknown, Chang Gung Memorial Hospital
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Synergistic Effects of Aerobic Exercise and Cognitive Training on Cognition in Stroke Patients With Cognitive Decline | ClinicalTrials.gov |
| NCT number | NCT02550990 | ClinicalTrials.gov |
| Status | Unknown | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 75 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Chang Gung Memorial Hospital | ClinicalTrials.gov |
| Conditions | Stroke Patients With Cognitive Decline | ClinicalTrials.gov |
| Interventions | Cognitive training, Aerobic exercise training, Sequential combination of aerobic exercise and cognitive training | ClinicalTrials.gov |
| First posted | 2015-09-16 | ClinicalTrials.gov |
| Last updated | 2016-12-20 | ClinicalTrials.gov |
Registered outcomes 25
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change scores of Montreal Cognitive Assessment (MoCA) | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Primary | Change scores of Wechsler Memory Scale - Third Edition (WMS-III) | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Primary | Change scores of Wechsler Adult Intelligence Scale - Third Edition (WAIS-III) | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Primary | Change scores of Useful Field of View (UFOV) | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Primary | Change scores of Stroop Color-Word test | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Primary | Change scores of Dual-task test | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | The dual-task tests will be assessed to determine the ability for an individual to perform 2 tasks simultaneously. The investigators will assess the dual-task performance during walking and performing box and block test. The results of the dual-task tests will provide information regarding to whether the 2 tasks compete for the same class of neural resources or one of the tasks can be carried out automatically. | ClinicalTrials.gov |
| Secondary | Change scores of serum BDNF level | Baseline, posttest (an expected average of 3 months) | ClinicalTrials.gov | |
| Secondary | Change scores of Antioxidative marker | Baseline, posttest (an expected average of 3 months) | Antioxidative markers will be used to reflect the changes on oxidative stress. In particular, we will be analyzing the total antioxidant capacity (TAC). | ClinicalTrials.gov |
| Secondary | Change scores of Glucose indicator | Baseline, posttest (an expected average of 3 months) | HbA1C level will be tested to investigate the relationships between blood glucose level and aerobic exercise. | ClinicalTrials.gov |
| Secondary | Change scores of Plasma lipid level | Baseline, posttest (an expected average of 3 months) | The cholesterol ratio (total cholesterol divided by high-density lipid) will be evaluated to reflect the lipid level in the blood. | ClinicalTrials.gov |
| Secondary | Change scores of Functional Independence Measure (FIM) | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Secondary | Change scores of Lawton Instrumental Activities of Daily Living Scale (Lawton IADL) | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Secondary | Change scores of Stroke Impact Scale (SIS) | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Secondary | Change scores of Caregiver Burden (CB) scale | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Secondary | Change scores of EuroQol (EQ)-5D questionnaire | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Secondary | Change scores of Timed up and go test (TUG) | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Secondary | Change scores of Six-minute walk test (6MWT) | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Secondary | Change scores of Mobility level | Baseline, posttest (an expected average of 3 months) | ClinicalTrials.gov | |
| Secondary | Change scores of International Physical Activity Questionnaires (IPAQ) | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov | |
| Secondary | Change scores of Fugl-Meyer Assessment (FMA) | Baseline, posttest (an expected average of 3 months), follow-up (up to 9 months) | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 2
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Field of View Speed Test | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)