Trial · NCT02558010
Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients
NCT02558010, Phase 3, Completed, Medical College of Wisconsin; results first posted 2023-04-27
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients. Trials, record NCT02558010. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02558010
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients
- NCT number
- NCT02558010
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 58 participants, actual
- Lead sponsor
- Medical College of Wisconsin
- Conditions
- Scoliosis, Pain
- Interventions
- Methadone, Normal Saline, Morphine
- First posted
- 2015-09-23
- Last updated
- 2023-11-18
- Results first posted
- 2023-04-27
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Post-operative Opioid Consumption (mg/kg) | 72 hours | Total amount of opioids consumed during the first 72 hours after surgery. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Post-operative Opioid Consumption (mg/kg) | 72 hours | All participants allocated to study groups, and received the intervention. | mg/kg | MEDIAN |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Post-operative Opioid Consumption (mg/kg) | Methadone Group | 0.267 | Inter-Quartile Range 0.119 to 0.451 | mg/kg | |
| Post-operative Opioid Consumption (mg/kg) | Control Group | 0.340 | Inter-Quartile Range 0.168 to 0.607 | mg/kg |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Methadone Group | 30 | |
| Overall Study | STARTED | Control Group | 28 | |
| Overall Study | COMPLETED | Methadone Group | 25 | |
| Overall Study | COMPLETED | Control Group | 22 | |
| Overall Study | NOT COMPLETED | Methadone Group | 5 | |
| Overall Study | NOT COMPLETED | Control Group | 6 |
Source ClinicalTrials.gov
Adverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Respiratory depression | Respiratory, thoracic and mediastinal disorders | Methadone Group | 1 | 25 | 1 |
| other | Respiratory depression | Respiratory, thoracic and mediastinal disorders | Control Group | 0 | 22 | 0 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Methadone Group | 0 | 25 |
| Total, all-cause mortality | Control Group | 0 | 22 |
| Total, other adverse events | Methadone Group | 1 | 25 |
| Total, other adverse events | Control Group | 0 | 22 |
| Total, serious adverse events | Methadone Group | 0 | 25 |
| Total, serious adverse events | Control Group | 0 | 22 |
Source ClinicalTrials.gov
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Methadone Group vs Control Group: deaths from any cause | Trial comparisons |
| Methadone Group vs Control Group: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02558010
GET https://conductscience.org/api/trials/v1/NCT02558010/registered