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Trial · NCT02564263

Results by group22

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Overall Survival (OS) in Participants With Squamous Cell Carcinoma (SCC) of the EsophagusPembrolizumab8.295% Confidence Interval 6.7 to 10.3Months
Overall Survival (OS) in Participants With Squamous Cell Carcinoma (SCC) of the EsophagusChemotherapy7.195% Confidence Interval 6.1 to 8.2Months
Overall Survival (OS) in Participants With Programmed Death-Ligand 1 Combined Positive Score ≥10 (PD-L1 CPS ≥10)Pembrolizumab9.395% Confidence Interval 6.6 to 12.5Months
Overall Survival (OS) in Participants With Programmed Death-Ligand 1 Combined Positive Score ≥10 (PD-L1 CPS ≥10)Chemotherapy6.795% Confidence Interval 5.1 to 8.2Months
Overall Survival (OS) in All ParticipantsPembrolizumab7.195% Confidence Interval 6.2 to 8.1Months
Overall Survival (OS) in All ParticipantsChemotherapy7.195% Confidence Interval 6.3 to 8.0Months
Progression-free Survival (PFS) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in All ParticipantsPembrolizumab2.195% Confidence Interval 2.1 to 2.2Months
Progression-free Survival (PFS) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in All ParticipantsChemotherapy3.495% Confidence Interval 2.8 to 3.9Months
Objective Response Rate (ORR) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in All ParticipantsPembrolizumab13.195% Confidence Interval 9.5 to 17.3Percentage of Participants
Objective Response Rate (ORR) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in All ParticipantsChemotherapy6.795% Confidence Interval 4.2 to 10.0Percentage of Participants
Progression-free Survival (PFS) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in Participants With Squamous Cell Carcinoma (SCC) of the EsophagusPembrolizumab2.295% Confidence Interval 2.1 to 3.2Months
Progression-free Survival (PFS) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in Participants With Squamous Cell Carcinoma (SCC) of the EsophagusChemotherapy3.195% Confidence Interval 2.2 to 3.9Months
Progression-free Survival (PFS) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in Participants With Programmed Death-Ligand 1 Combined Positive Score ≥10 (PD-L1 CPS ≥10)
Pembrolizumab2.695% Confidence Interval 2.1 to 4.1Months
Progression-free Survival (PFS) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in Participants With Programmed Death-Ligand 1 Combined Positive Score ≥10 (PD-L1 CPS ≥10)
Chemotherapy3.095% Confidence Interval 2.1 to 3.7Months
Objective Response Rate (ORR) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in Participants With Squamous Cell Carcinoma (SCC) of the EsophagusPembrolizumab16.795% Confidence Interval 11.8 to 22.6Percentage of Participants
Objective Response Rate (ORR) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in Participants With Squamous Cell Carcinoma (SCC) of the EsophagusChemotherapy7.495% Confidence Interval 4.2 to 11.9Percentage of Participants
Objective Response Rate (ORR) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in Participants With Programmed Death-Ligand 1 Combined Positive Score ≥10 (PD-L1 CPS ≥10)
Pembrolizumab21.595% Confidence Interval 14.1 to 30.5Percentage of Participants
Objective Response Rate (ORR) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) in Participants With Programmed Death-Ligand 1 Combined Positive Score ≥10 (PD-L1 CPS ≥10)
Chemotherapy6.195% Confidence Interval 2.5 to 12.1Percentage of Participants
Number of Participants Experiencing an Adverse Event (AE)Pembrolizumab301Participants
Number of Participants Experiencing an Adverse Event (AE)Chemotherapy288Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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