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Trial · NCT02590874

The Use of Duloxetine for Cognition Improvement in Individuals With Mild Cognitive Impairment

NCT02590874, Phase 4, Completed, University of North Texas Health Science Center

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. The Use of Duloxetine for Cognition Improvement in Individuals With Mild Cognitive Impairment. Trials, record NCT02590874. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02590874

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
The Use of Duloxetine for Cognition Improvement in Individuals With Mild Cognitive Impairment
NCT number
NCT02590874
Status
Completed
Phases
Phase 4
Enrollment
19 participants, actual
Lead sponsor
University of North Texas Health Science Center
Conditions
Mild Cognitive Impairment, Depression
Interventions
Duloxetine, Placebo
First posted
2015-10-29
Last updated
2018-10-11

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange in scores for the Repeatable Battery for Neuropsychological Status (RBANS) from baseline to 16 weeks.Weeks 0 and 16RBANS measures immediate memory, visuospatial construction, attention processes and speed of information processing, expressive and receptive language, and delayed memory.
SecondaryEvaluation of the relative dominance of the verbal-reading system from baseline at 16 weeks through the Stroop Color and Word TestWeeks 0 and 16The Stroop is associated with cognitive flexibility, resistance to interference from outside stimuli, creativity, and psychopathology

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers5

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
22653735BACKGROUNDPubMed
22976076BACKGROUNDPubMed
23643456BACKGROUNDPubMed
23874786BACKGROUNDPubMed
25394326BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests1

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

TestNamed as
Stroop Color-Word TestSecondary outcome

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT02590874

GET https://conductscience.org/api/trials/v1/NCT02590874/registered