Trial · NCT02600390
SANGUINATE™ in Sickle Cell Disease Associated Leg Ulcer
NCT02600390, Phase 2, Completed, Prolong Pharmaceuticals
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. SANGUINATE™ in Sickle Cell Disease Associated Leg Ulcer. Trials, record NCT02600390. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02600390
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- SANGUINATE™ in Sickle Cell Disease Associated Leg Ulcer
- NCT number
- NCT02600390
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 10 participants, actual
- Lead sponsor
- Prolong Pharmaceuticals
- Conditions
- Leg Ulcer
- Interventions
- SANGUINATE
- First posted
- 2015-11-09
- Last updated
- 2017-02-28
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Safety of treatment as determined by changes in vital signs, electrocardiographic, biochemical, hematological, and urinalysis measures, and reported adverse events | 8 or 10 weeks | |
| Primary | Change in Sickle Cell Disease leg ulcer wound pain scores as measured by a 10-point scale, relative to non-wound site pain scores | 8 or 10 weeks | |
| Primary | Rate and extent of leg ulcer wound healing as measured by change in wound surface area | 8 or 10 weeks | |
| Secondary | Changes in leg ulcer wound status as measured by need for debridement (type and quantity of non-viable tissue) | 8 or 10 weeks | |
| Secondary | Changes in leg ulcer wound status as measured by extent of exudate production | 8 or 10 weeks | Change in quality of life as measured by SF-12 Health Survey (acute version) as well as other indicators of patient comfort and well-being |
| Secondary | Changes in leg ulcer wound status as measured by type and amount of granulation tissue | 8 or 10 weeks | |
| Secondary | Changes in leg ulcer wound status as measured by overall change in leg ulcer wound appearance | 8 or 10 weeks | |
| Secondary | Change in local skin in the region of the leg ulcer as measured by skin appearance (coloration, inflammation, etc.) | 8 or 10 weeks | |
| Secondary | Change in local skin in the region of the leg ulcer as measured by skin temperature (relative to body temperature) | 8 or 10 weeks | |
| Secondary | Improvement in leg ulcer wound severity as measured by Venous Clinical Severity Score (VCSS) | 8 or 10 weeks |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02600390
GET https://conductscience.org/api/trials/v1/NCT02600390/registered