Trial · NCT02612480
Registered outcomes22
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 20 of 22
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | concentration plasma TNFalpha (pg/ml) | measured after challenge with endotoxin at day 7 of medication | measured with Luminex assay |
| Secondary | concentration plasma IL-6 (pg/ml) | measured after challenge with endotoxin at day 7 of medication | measured with Luminex assay |
| Secondary | concentration plasma IL-8 (pg/ml) | measured after challenge with endotoxin at day 7 of medication | measured with Luminex assay |
| Secondary | concentration plasma IL-10 (pg/ml) | measured after challenge with endotoxin at day 7 of medication | measured with Luminex assay |
| Secondary | concentration plasma IL-1RA (pg/ml) | measured after challenge with endotoxin at day 7 of medication | measured with Luminex assay |
| Secondary | concentration plasma IL-1beta (pg/ml) | measured after challenge with endotoxin at day 7 of medication | measured with Luminex assay |
| Secondary | concentration plasma MCP-1(pg/ml) | measured after challenge with endotoxin at day 7 of medication | measured with Luminex assay |
| Secondary | concentration plasma MIP-1a(pg/ml) | measured after challenge with endotoxin at day 7 of medication | measured with Luminex assay |
| Secondary | concentration plasma MIP-1b(pg/ml) | measured after challenge with endotoxin at day 7 of medication | |
| Secondary | concentration plasma IFNgamma(pg/ml) | measured after challenge with endotoxin at day 7 of medication | measured with Luminex assay |
| Secondary | plasma adenosine | measured after challenge with endotoxin at day 7 of medication | |
| Secondary | platelet monocyte complexes | measured after challenge with endotoxin at day 7 of medication | flowcytometric determination of monocytic load with platelets |
| Secondary | platelet neutrophil complexes | measured after challenge with endotoxin at day 7 of medication | flowcytometric determination of neutrophil load with platelets |
| Secondary | platelet reactivity | measured after challenge with endotoxin at day 7 of medication | ex vivo stimulation of platelets with ADP and collagen, response measured as P-selectin and fibrinogen) |
| Secondary | monocytic tissue factor expression | measured after challenge with endotoxin at day 7 of medication | tissue factor expression on monocytes as measured by flow cytometry |
| Secondary | monocytic HLA-DR expression | measured after challenge with endotoxin at day 7 of medication | as measured by flow cytometry |
| Secondary | CD14/16 ratio | measured after challenge with endotoxin at day 7 of medication | measured with flow cytometry |
| Secondary | platelet von Willebrandfactor expression | measured after challenge with endotoxin at day 7 of medication | measured with flow cytometry |
| Secondary | VASP-P | difference between measurement prior to start of study drug after challenge with endotoxin at day 7 of medication | ELISA |
| Secondary | symptoms during endotoxin day | measured after challenge with endotoxin at day 7 of medication | 6 point likert scale |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
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