Trial · NCT02614937
Study of Squalamine Lactate for the Treatment of Macular Edema Related to Retinal Vein Occlusion
NCT02614937, Phase 1, Phase 2, Completed, Ohr Pharmaceutical Inc.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Study of Squalamine Lactate for the Treatment of Macular Edema Related to Retinal Vein Occlusion. Trials, record NCT02614937. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02614937
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Study of Squalamine Lactate for the Treatment of Macular Edema Related to Retinal Vein Occlusion
- NCT number
- NCT02614937
- Status
- Completed
- Phases
- Phase 1, Phase 2
- Enrollment
- 20 participants, actual
- Lead sponsor
- Ohr Pharmaceutical Inc.
- Conditions
- Retinal Vein Occlusion, Macular Edema
- Interventions
- ranibizumab, Squalamine Lactate Ophthalmic Solution, 0.2%
- First posted
- 2015-11-25
- Last updated
- 2015-11-25
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Visual Function - Efficacy | Baseline to Week 38 | Mean change in ETDRS letter score from baseline |
| Secondary | Visual Function - Efficacy | Baseline to Week 38 | Eyes with visual outcomes of 20/40 or better at Week 38 compared to Baseline Visit |
| Secondary | Retinal Anatomy - Efficacy | Baseline to Week 38 | Proportion of eyes with Central Subfield Thickness (CST) on SD-OCT less than 325 microns at Week 38 |
| Secondary | Safety and Tolerability as measured by adverse event reporting and ophthalmologic examination from Baseline to Week 38 | Baseline to Week 38 | Safety as measured by adverse event reporting and ophthalmologic examination from Baseline to Week 38 |
| Secondary | Concomitant ranibizumab administration - efficacy | Baseline to Week 38 | Number of injections of 0.5 mg ranibizumab to keep edema resolved from Week 2 through Week 34 of study |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02614937
GET https://conductscience.org/api/trials/v1/NCT02614937/registered