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Trial · NCT02616393

Results by group64

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Best Overall Response Rate (ORR) of Subjects With BMCohort A (BM)CNS15.495% Confidence Interval 2 to 45Percentage of participants (%)
Best Overall Response Rate (ORR) of Subjects With BMCohort C (BM-IP)CNS10095% Confidence Interval 29 to 100Percentage of participants (%)
Best Overall Response Rate (ORR) of Subjects With BMOverall BMCNS31.395% Confidence Interval 11 to 59Percentage of participants (%)
Best Overall Response Rate (ORR) of Subjects With BMCohort A (BM)non-CNS095% Confidence Interval 0 to 25Percentage of participants (%)
Best Overall Response Rate (ORR) of Subjects With BMCohort C (BM-IP)non-CNS10095% Confidence Interval 29 to 100Percentage of participants (%)
Best Overall Response Rate (ORR) of Subjects With BMOverall BMnon-CNS18.895% Confidence Interval 4 to 46Percentage of participants (%)
Best Overall Response Rate (ORR) of Subjects With BMCohort A (BM)CNS + non-CNS15.495% Confidence Interval 2 to 45Percentage of participants (%)
Best Overall Response Rate (ORR) of Subjects With BMCohort C (BM-IP)CNS + non-CNS10095% Confidence Interval 29 to 100Percentage of participants (%)
Best Overall Response Rate (ORR) of Subjects With BMOverall BMCNS + non-CNS31.395% Confidence Interval 11 to 59Percentage of participants (%)
Best ORR of Subjects With LMCohort B (LM)0Percentage of participants (%)
Median Progression-free Survival (PFS)Cohort A (BM)9.2995% Confidence Interval 4.14 to 27.43Weeks
Median Progression-free Survival (PFS)Cohort B (LM)10.8695% Confidence Interval 6.86 to 17.14Weeks
Median Progression-free Survival (PFS)Cohort C (BM-IP)37.7195% Confidence Interval 20.14 to 62.14Weeks
Probability of PFS at 12 Weeks and 24 Weeks--Cohort A (BM Only) and Cohort B (LM Only)Cohort A (BM)12 weeks (3 months)0.476295% Confidence Interval 0.1823 to 0.7237Probability
Probability of PFS at 12 Weeks and 24 Weeks--Cohort A (BM Only) and Cohort B (LM Only)Cohort B (LM)12 weeks (3 months)0.473795% Confidence Interval 0.2444 to 0.6728Probability
Probability of PFS at 12 Weeks and 24 Weeks--Cohort A (BM Only) and Cohort B (LM Only)Cohort A (BM)24 weeks (6 months)0.285795% Confidence Interval 0.0698 to 0.5546Probability
Probability of PFS at 12 Weeks and 24 Weeks--Cohort A (BM Only) and Cohort B (LM Only)Cohort B (LM)24 weeks (6 months)0.263295% Confidence Interval 0.0958 to 0.4677Probability
Probability of PFS at 24 Weeks--Cohort C (BM-IP Only)Cohort C (BM-IP)0.666795% Confidence Interval 0.0541 to 0.9452Probability
Probability of OS at 12 Weeks and at 24 Weeks--Cohort A (BM Only) and Cohort B (LM Only)Cohort A (BM)12 weeks (3 months)0.846295% Confidence Interval 0.5122 to 0.9591Probability
Probability of OS at 12 Weeks and at 24 Weeks--Cohort A (BM Only) and Cohort B (LM Only)Cohort B (LM)12 weeks (3 months)0.847195% Confidence Interval 0.5968 to 0.9480Probability

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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