Trial · NCT02635828
Effectiveness of Triple Therapy With Palonosetron for PON Prophylaxis
NCT02635828, Phase 4, Completed, Ohio State University; results first posted 2017-05-05
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effectiveness of Triple Therapy With Palonosetron for PON Prophylaxis. Trials, record NCT02635828. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02635828
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effectiveness of Triple Therapy With Palonosetron for PON Prophylaxis
- NCT number
- NCT02635828
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 40 participants, actual
- Lead sponsor
- Ohio State University
- Conditions
- Postoperative Nausea and Vomiting
- Interventions
- Palonosetron 0.075 mg IV, Dexamethasone 10 mg IV, Promethazine 25 mg IV
- First posted
- 2015-12-21
- Last updated
- 2017-05-05
- Results first posted
- 2017-05-05
- Limitations and caveats
Our study also presented certain limitations that should be mentioned. To begin with, the study was designed without a control group; therefore, we were not able to compare the results from this regimen.
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | PONV Incidence | 24 hours after end of surgery | The incidence of PONV |
| Secondary | Incidence of Subjects Significant QTc Changes in the EKG | 24 and 120 hours/discharge after end of surgery | The incidence of significant QTc prolongation was measured by comparing baseline EKG, 24 hours and 120 hours after surgery |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | PONV Incidence | 24 hours after end of surgery | Incidence of PONV | participants | NUMBER |
| SECONDARY | Incidence of Subjects Significant QTc Changes in the EKG | 24 and 120 hours/discharge after end of surgery | participants | NUMBER |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| PONV Incidence | Triple Therapy PONV Prohylaxis | 12 | participants | ||
| Incidence of Subjects Significant QTc Changes in the EKG | Triple Therapy PONV Prohylaxis | 0 | participants |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Triple Therapy PONV Prohylaxis | 54 | |
| Overall Study | COMPLETED | Triple Therapy PONV Prohylaxis | 40 | |
| Overall Study | NOT COMPLETED | Triple Therapy PONV Prohylaxis | 14 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Triple Therapy PONV Prohylaxis | ||
| Total, other adverse events | Triple Therapy PONV Prohylaxis | 0 | 40 |
| Total, serious adverse events | Triple Therapy PONV Prohylaxis | 0 | 40 |
Source ClinicalTrials.gov
Papers20
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02635828
GET https://conductscience.org/api/trials/v1/NCT02635828/registered