Trial · NCT02648698
RCT(Randomized Clinical Trial ) of Antibiotic Therapy in Chronic Endometritis
NCT02648698, Not applicable, Completed, Fu Xing Hospital, Capital Medical University; results first posted 2020-06-04
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. RCT(Randomized Clinical Trial ) of Antibiotic Therapy in Chronic Endometritis. Trials, record NCT02648698. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02648698
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- RCT(Randomized Clinical Trial ) of Antibiotic Therapy in Chronic Endometritis
- NCT number
- NCT02648698
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 120 participants, actual
- Lead sponsor
- Fu Xing Hospital, Capital Medical University
- Conditions
- Chronic Endometritis
- Interventions
- Antibiotics
- First posted
- 2016-01-07
- Last updated
- 2022-02-07
- Results first posted
- 2020-06-04
- Limitations and caveats
A possible limitation of our study is that patients were not blinded to the antibiotic treatment. A further limitation is the cure rate based on a repeat of test used to make the diagnosis, instead of pregnancy, miscarriage or live birth.
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The Conversion Rate of CE (From Positive to Negative) | 1-6 months | Subjects in antibiotic group underwent a second-look hysteroscopy and repeat endometrial biopsy for histopathological CD138 immunohistochemical examination 2-4 weeks after completion of antibiotic treatment and in the follicular phase of the following menstrual cycle. Subjects in control group underwent a second-look hysteroscopy and repeat endometrial biopsy for histopathological CD138 immunohistochemical examination \~4 weeks after recruitment in the follicular phase of the following menstrual cycle. The biopsies were graded as "negative" for CE if there was less than one plasma cell identified per 10 high-power fields (HPFs) and "positive" when there was one or more plasma cell identified per 10 HPFs. To compare the cure rate (From positive to negative) of CE in women who received antibiotic therapy (treatment group) with the spontaneous cure rate in those who did not receive antibiotic therapy (control group), |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | The Conversion Rate of CE (From Positive to Negative) | 1-6 months | Percentage of participants | NUMBER |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| The Conversion Rate of CE (From Positive to Negative) | Antibiotic Group | 89.8 | 95% Confidence Interval 82.2 to 97.5 | Percentage of participants | |
| The Conversion Rate of CE (From Positive to Negative) | Control Group | 12.7 | 95% Confidence Interval 3.9 to 21.5 | Percentage of participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Antibiotic Group | 60 | |
| Overall Study | STARTED | Control Group | 60 | |
| Overall Study | COMPLETED | Antibiotic Group | 59 | |
| Overall Study | COMPLETED | Control Group | 55 | |
| Overall Study | NOT COMPLETED | Antibiotic Group | 1 | |
| Overall Study | NOT COMPLETED | Control Group | 5 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Antibiotic Group | 0 | 59 |
| Total, all-cause mortality | Control Group | 0 | 55 |
| Total, other adverse events | Antibiotic Group | 0 | 59 |
| Total, other adverse events | Control Group | 0 | 55 |
| Total, serious adverse events | Antibiotic Group | 0 | 59 |
| Total, serious adverse events | Control Group | 0 | 55 |
Source ClinicalTrials.gov
Papers9
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Antibiotic Group vs Control Group: deaths from any cause | Trial comparisons |
| Antibiotic Group vs Control Group: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02648698
GET https://conductscience.org/api/trials/v1/NCT02648698/registered