Trial · NCT02659488
Lisdexamfetamine in Binge Eating Disorder (BED): fMRI Effects
NCT02659488, Phase 2, Unknown, Lindner Center of HOPE
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Lisdexamfetamine in Binge Eating Disorder (BED): fMRI Effects. Trials, record NCT02659488. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02659488
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Lisdexamfetamine in Binge Eating Disorder (BED): fMRI Effects
- NCT number
- NCT02659488
- Status
- Unknown
- Phases
- Phase 2
- Enrollment
- 40 participants, estimated
- Lead sponsor
- Lindner Center of HOPE
- Conditions
- Binge Eating Disorder
- Interventions
- Lisdexamfetamine
- First posted
- 2016-01-20
- Last updated
- 2016-01-20
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Measurement of ventral prefrontal, striatal, and amygdala brain activation, assessed using food cues. | Change from baseline to 12 weeks of brain activation | Investigators will statistically compare the brain response to food pictures of BED patients before and after receiving 12 weeks of LDX treatment. |
| Secondary | Clinical Global Impression Improvement Scale (CGI-I) | weeks 1, 2, 3, 4, 6, 8, 10, 12 | score between 1-7 (1 = very much improved, ranging to 7 = very much worse) |
| Secondary | Yale Brown Obsessive-Compulsive Scale modified for binge eating (YBOC-BE) | weeks 0,1, 2, 3, 4, 6, 8, 10, 12 | Will examine to see if severity of YBOC-BE scores correlate with fMRI abnormalities at baseline; and whether improvement in this scale with LDX treatment correlate with improvement in fMRI abnormalities at Endpoint. |
| Secondary | Binge Eating Scale (BES) | weeks 0,1, 2, 3, 4, 6, 8, 10, 12 | Will examine to see if severity of BES scores correlate with fMRI abnormalities at baseline; and whether improvement in this scale with LDX treatment correlate with improvement in fMRI abnormalities at Endpoint. |
| Secondary | Weight | weeks 0,1, 2, 3, 4, 6, 8, 10, 12 | measured in kilograms |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02659488
GET https://conductscience.org/api/trials/v1/NCT02659488/registered