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Trial · NCT02671435

Participant flow60

How many started, completed or left each group, period by period.

PeriodMilestoneGroupParticipantsUnits counted
Overall StudySTARTEDDose-escalation Cohort 1: Monalizumab 22.5 mg Q2W + Durvalumab 1500 mg Q4W3
Overall StudySTARTEDDose-escalation Cohort 2: Monalizumab 75 mg Q2W + Durvalumab 1500 mg Q4W3
Overall StudySTARTEDDose-escalation Cohort 3: Monalizumab 225 mg Q2W + Durvalumab 1500 mg Q4W3
Overall StudySTARTEDDose-escalation Cohort 4: Monalizumab 750 mg Q2W + Durvalumab 1500 mg Q4W18
Overall StudySTARTEDDose-escalation Cohort 5: Monalizumab 750 mg Q4W + Durvalumab 1500 mg Q4W18
Overall StudySTARTEDDose-expansion Cohort: Monalizumab 750 mg Q2W + Durvalumab 1500 mg Q4W (MSS-CRC)40
Overall StudySTARTEDDose-expansion Cohort: Monalizumab 750 mg Q2W + Durvalumab 1500 mg Q4W (Ovarian)40
Overall StudySTARTEDDose-expansion Cohort: Monalizumab 750 mg Q2W + Durvalumab 1500 mg Q4W (Endometrial MSS)40
Overall StudySTARTEDDose-expansion Cohort: Monalizumab 750 mg Q2W + Durvalumab 1500 mg Q4W (NSCLC)20
Overall StudySTARTEDExploration Cohort A1: Monalizumab 750 mg Q2W+Durvalumab 1500 mg Q4W+mFOLFOX6 Q2W+Bevacizumab Q2W18
Overall StudySTARTEDExploration CohortA2: Monalizumab 750 mg Q2W + Durvalumab 1500 mg Q4W + mFOLFOX6 Q2W + Cetuximab Q2W18
Overall StudySTARTEDExploration Cohort C1A: Monalizumab 750 mg Q2W + Durvalumab 1500 mg Q4W + Cetuximab Q2W40
Overall StudySTARTEDExploration Cohort C1B: Monalizumab 750 mg Q2W + Cetuximab Q2W41
Overall StudySTARTEDExploration Cohort C2A: Monalizumab 750 mg Q2W + Durvalumab 1500 mg Q4W + Cetuximab Q2W44
Overall StudySTARTEDExploration Cohort C2B: Monalizumab 750 mg Q2W + Cetuximab Q2W37
Overall StudyTreatedDose-escalation Cohort 1: Monalizumab 22.5 mg Q2W + Durvalumab 1500 mg Q4W3
Overall StudyTreatedDose-escalation Cohort 2: Monalizumab 75 mg Q2W + Durvalumab 1500 mg Q4W3
Overall StudyTreatedDose-escalation Cohort 3: Monalizumab 225 mg Q2W + Durvalumab 1500 mg Q4W3
Overall StudyTreatedDose-escalation Cohort 4: Monalizumab 750 mg Q2W + Durvalumab 1500 mg Q4W18
Overall StudyTreatedDose-escalation Cohort 5: Monalizumab 750 mg Q4W + Durvalumab 1500 mg Q4W18

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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