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First-In-Human Study to Evaluate Safety, Tolerability, and PK of Intravenous ATB200 Alone and When Co-Administered With Oral AT2221
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Trial · NCT02675465

Participant flow72

How many started, completed or left each group, period by period.

61 to 72 of 72

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PeriodMilestoneGroupParticipantsUnits counted
Stage 4: Long Term ExtensionCOMPLETEDCohort 1 (ERT Experienced; Ambulatory): SAD 5 to 20 mg/kg ATB2000
Stage 4: Long Term ExtensionCOMPLETEDCohort 1 (ERT Experienced; Ambulatory) MAD 20 mg/kg ATB200 + 130 to 260 mg AT22210
Stage 4: Long Term ExtensionCOMPLETEDCohort 1 (ERT Experienced; Ambulatory):8
Stage 4: Long Term ExtensionCOMPLETEDCohort 2 (ERT Experienced; Non-ambulatory): 20 mg/kg ATB200 + 260 mg AT22214
Stage 4: Long Term ExtensionCOMPLETEDCohort 3 (ERT Naive; Ambulatory): 20 mg/kg ATB200 + 260 mg AT22216
Stage 4: Long Term ExtensionCOMPLETEDCohort 4 (ERT Experienced; Ambulatory): 20 mg/kg ATB200 + 260 mg AT22216
Stage 4: Long Term ExtensionNOT COMPLETEDCohort 1 (ERT Experienced; Ambulatory): SAD 5 to 20 mg/kg ATB2000
Stage 4: Long Term ExtensionNOT COMPLETEDCohort 1 (ERT Experienced; Ambulatory) MAD 20 mg/kg ATB200 + 130 to 260 mg AT22210
Stage 4: Long Term ExtensionNOT COMPLETEDCohort 1 (ERT Experienced; Ambulatory):1
Stage 4: Long Term ExtensionNOT COMPLETEDCohort 2 (ERT Experienced; Non-ambulatory): 20 mg/kg ATB200 + 260 mg AT22211
Stage 4: Long Term ExtensionNOT COMPLETEDCohort 3 (ERT Naive; Ambulatory): 20 mg/kg ATB200 + 260 mg AT22210
Stage 4: Long Term ExtensionNOT COMPLETEDCohort 4 (ERT Experienced; Ambulatory): 20 mg/kg ATB200 + 260 mg AT22210

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

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Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/trials/v1/NCT02675465/flow?page=4

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