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Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors
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Trial · NCT02684058

Participant flow39

How many started, completed or left each group, period by period.

1 to 20 of 39

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PeriodMilestoneGroupParticipantsUnits counted
Treatment PeriodSTARTEDLGG Cohort: Dabrafenib and Trametinib73
Treatment PeriodSTARTEDLGG Cohort: Carboplatin and Vincristine37
Treatment PeriodSTARTEDHGG Cohort: Dabrafenib and Trametinib41
Treatment PeriodTreatedLGG Cohort: Dabrafenib and Trametinib73
Treatment PeriodTreatedLGG Cohort: Carboplatin and Vincristine33
Treatment PeriodTreatedHGG Cohort: Dabrafenib and Trametinib41
Treatment PeriodCOMPLETEDLGG Cohort: Dabrafenib and Trametinib56
Treatment PeriodCOMPLETEDLGG Cohort: Carboplatin and Vincristine14
Treatment PeriodCOMPLETEDHGG Cohort: Dabrafenib and Trametinib17
Treatment PeriodNOT COMPLETEDLGG Cohort: Dabrafenib and Trametinib17
Treatment PeriodNOT COMPLETEDLGG Cohort: Carboplatin and Vincristine23
Treatment PeriodNOT COMPLETEDHGG Cohort: Dabrafenib and Trametinib24
Post-treatment Efficacy Follow-upSTARTEDLGG Cohort: Dabrafenib and Trametinib9
Post-treatment Efficacy Follow-upSTARTEDLGG Cohort: Carboplatin and Vincristine22
Post-treatment Efficacy Follow-upSTARTEDHGG Cohort: Dabrafenib and Trametinib5
Post-treatment Efficacy Follow-upCOMPLETEDLGG Cohort: Dabrafenib and Trametinib2
Post-treatment Efficacy Follow-upCOMPLETEDLGG Cohort: Carboplatin and Vincristine14
Post-treatment Efficacy Follow-upCOMPLETEDHGG Cohort: Dabrafenib and Trametinib2
Post-treatment Efficacy Follow-upNOT COMPLETEDLGG Cohort: Dabrafenib and Trametinib7
Post-treatment Efficacy Follow-upNOT COMPLETEDLGG Cohort: Carboplatin and Vincristine8

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

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Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT02684058/flow

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