Trial · NCT02684942
Comparison of Meperidine and Fentanyl on Pain Scale and QOL in Brachytherapy
NCT02684942, Phase 4, Completed, Chulabhorn Cancer Center; results first posted 2017-06-01
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparison of Meperidine and Fentanyl on Pain Scale and QOL in Brachytherapy. Trials, record NCT02684942. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02684942
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparison of Meperidine and Fentanyl on Pain Scale and QOL in Brachytherapy
- NCT number
- NCT02684942
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 40 participants, actual
- Lead sponsor
- Chulabhorn Cancer Center
- Conditions
- Pain, Quality of Life
- Interventions
- Meperidine, Fentanyl
- First posted
- 2016-02-18
- Last updated
- 2017-06-01
- Results first posted
- 2017-06-01
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Pain Score | From date of the first fraction until date of the last fraction of brachytherapy, once a week for four weeks | Perceived pain score according to standard 10-cm visual analog scales (VAS) was assessed before injection of medicine for every 15 minutes up to 120 minutes.The minimum and maximum scores were 0, 10. Score 0 means no pain, 1-3 mild pain, 4-6 moderate pain, 7-9 severe pain and 10 worst pain. |
| Secondary | Quality of Life | From date of the first fraction of brachytherapy until date of the last fraction of brachytherapy,once a week for 4 weeks | Perceived Quality of life (EQ-5D) was assessed before the first brachytherpy and immediately after completion of each of the 4 brachytherapy fractions. The EQ-5D have 5 dimensions: mobility, self-care, usual activities, topics each content 3 responses: no problems, some problems, extreme problems. |
| Other | Ovoids Size | after complete applicator insertion. | Size of ovoids that a pair part of brachytherapy applicator insert in vagina trough cervix. |
| Other | Tumor Size | Before insert applicator in each fraction of brachytherapy. | Size of tumor at cervix measured by the doctor before insert applicator. |
| Other | Meperidine Dose | after complete treatment. | Sum of meperidine dose when finish each fraction of brachytherapy |
| Other | Fentanyl Dose | after complete treatment. | Sum of fentanyl dose when finish each fraction of brachytherapy |
Source ClinicalTrials.gov
Outcomes6
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Pain Score | From date of the first fraction until date of the last fraction of brachytherapy, once a week for four weeks | units on a scale | MEAN | |
| SECONDARY | Quality of Life | From date of the first fraction of brachytherapy until date of the last fraction of brachytherapy,once a week for 4 weeks | Pain score in each fraction. | participants | NUMBER |
| OTHER_PRE_SPECIFIED | Ovoids Size | after complete applicator insertion. | Each patient was treated with 4 fractions of brachytherapy. | Centimeter | MEDIAN |
| OTHER_PRE_SPECIFIED | Tumor Size | Before insert applicator in each fraction of brachytherapy. | Participants received 4 fraction of brachytherapy. Thus all 160 fractions separated to two group of drug and analysis data in each group. | CM. | MEAN |
| OTHER_PRE_SPECIFIED | Meperidine Dose | after complete treatment. | Participants received 4 fraction of brachytherapy. Thus all 160 fractions separated to two group of drug and analysis data in each group. | mg. | MEAN |
| OTHER_PRE_SPECIFIED | Fentanyl Dose | after complete treatment. | Participants received 4 fraction of brachytherapy. Thus all 160 fractions separated to two group of drug and analysis data in each group. | ug. | MEAN |
Source ClinicalTrials.gov
Results by group56
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Pain Score | Meperidine | baseline | 0.04 | Standard Deviation 0.25 | units on a scale |
| Pain Score | Fentanyl | baseline | 0.14 | Standard Deviation 0.55 | units on a scale |
| Pain Score | Meperidine | 0 minute | 0.49 | Standard Deviation 1.18 | units on a scale |
| Pain Score | Fentanyl | 0 minute | 0.40 | Standard Deviation 1.16 | units on a scale |
| Pain Score | Meperidine | 15 minute | 0.59 | Standard Deviation 1.38 | units on a scale |
| Pain Score | Fentanyl | 15 minute | 0.65 | Standard Deviation 1.21 | units on a scale |
| Pain Score | Meperidine | 30 minute | 1.05 | Standard Deviation 1.76 | units on a scale |
| Pain Score | Fentanyl | 30 minute | 1.24 | Standard Deviation 2.21 | units on a scale |
| Pain Score | Meperidine | 45 minute | 1.33 | Standard Deviation 2.09 | units on a scale |
| Pain Score | Fentanyl | 45 minute | 1.70 | Standard Deviation 2.48 | units on a scale |
1 to 10 of 56Source ClinicalTrials.gov
See all 56 results by groupParticipant flow18
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Meperidine,Fentanyl,Meperidine,Fentanyl | 7 | |
| Overall Study | STARTED | Fentanyl,Meperidine,Fentanyl,Meperidine | 7 | |
| Overall Study | STARTED | Meperidine,Meperidine,Fentanyl,Fentanyl | 7 | |
| Overall Study | STARTED | Fentanyl,Fentanyl,Meperidine,Meperidine | 7 | |
| Overall Study | STARTED | Meperidine,Fentanyl,Fentanyl,Meperidine | 6 | |
| Overall Study | STARTED | Fentanyl,Meperidine,Meperidine,Fentanyl | 6 | |
| Overall Study | COMPLETED | Meperidine,Fentanyl,Meperidine,Fentanyl | 7 | |
| Overall Study | COMPLETED | Fentanyl,Meperidine,Fentanyl,Meperidine | 7 | |
| Overall Study | COMPLETED | Meperidine,Meperidine,Fentanyl,Fentanyl | 7 | |
| Overall Study | COMPLETED | Fentanyl,Fentanyl,Meperidine,Meperidine | 7 |
1 to 10 of 18Source ClinicalTrials.gov
See all 18 participant flowAdverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Meperidine | 0 | 40 |
| Total, all-cause mortality | Fentanyl | 0 | 40 |
| Total, other adverse events | Meperidine | 0 | 40 |
| Total, other adverse events | Fentanyl | 0 | 40 |
| Total, serious adverse events | Meperidine | 0 | 40 |
| Total, serious adverse events | Fentanyl | 0 | 40 |
Source ClinicalTrials.gov
Papers11
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Meperidine vs Fentanyl: deaths from any cause | Trial comparisons |
| Meperidine vs Fentanyl: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02684942
GET https://conductscience.org/api/trials/v1/NCT02684942/results?page=2