Trial · NCT02724228
A Study to Evaluate Long-Term Safety, Tolerability, & Efficacy of BMN 111 in Children With Achondroplasia (ACH)
NCT02724228, Phase 2, Active not recruiting, BioMarin Pharmaceutical
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Study to Evaluate Long-Term Safety, Tolerability, & Efficacy of BMN 111 in Children With Achondroplasia (ACH). Trials, record NCT02724228. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02724228
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study to Evaluate Long-Term Safety, Tolerability, & Efficacy of BMN 111 in Children With Achondroplasia (ACH)
- NCT number
- NCT02724228
- Status
- Active not recruiting
- Phases
- Phase 2
- Enrollment
- 30 participants, actual
- Lead sponsor
- BioMarin Pharmaceutical
- Conditions
- Achondroplasia
- Interventions
- BMN 111
- First posted
- 2016-03-31
- Last updated
- 2026-03-13
- Other registries' IDs
- eudract:2015-004004-30
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability] | Until near final adult height is reached, and up to at least 16 years of age for females and 18 years of age for males, whichever occurs later | * Number of study participants with treatment-emergent adverse events. * Number of study participants with treatment-emergent serious adverse events |
| Secondary | Growth Velocity [Efficacy] | Until near final adult height is reached | Annualized growth velocity (cm/yr) |
| Secondary | Growth Parameters (Efficacy) | Until near final adult height is reached, and up to at least 16 years of age for females and 18 years of age for males, whichever occurs later | Height standard score (Z-score) |
| Secondary | Body Proportions (Efficacy) | Until near final adult height is reached, and up to at least 16 years of age for females and 18 years of age for males, whichever occurs later | Upper-to-lower body segment ratio |
| Secondary | Final Adult Height | Up to at least 16 years of age for females and 18 years of age for males | Height at the age of 16 years for females and 18 years for males |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02724228
GET https://conductscience.org/api/trials/v1/NCT02724228/registered