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Trial · NCT02724566

Effect of Apelin on Insulin Sensitivity in Type 2 Diabetic Volunteers

NCT02724566, Phase 1, Completed, University Hospital, Toulouse

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Effect of Apelin on Insulin Sensitivity in Type 2 Diabetic Volunteers. Trials, record NCT02724566. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02724566

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Effect of Apelin on Insulin Sensitivity in Type 2 Diabetic Volunteers
NCT number
NCT02724566
Status
Completed
Phases
Phase 1
Enrollment
9 participants, actual
Lead sponsor
University Hospital, Toulouse
Conditions
Diabetes
Interventions
apelin, placebo
First posted
2016-03-31
Last updated
2025-12-10

Source ClinicalTrials.gov

Registered outcomes9

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryDelta between Glucose Infusion Rate240 minutes
Difference between glucose infusion rate measured during investigational product infusion (mean of values measured at 210, 215, 220, 225, 230, 235 and 240 minutes) and basal glucose infusion rate (mean of values measured at 90, 95, 100, 105, 110, 115 and 120 minutes).
SecondaryMeasure of M-value (a glucose physiological parameter)240 minutes
Difference between value of product time (mean of values measured at 210, 215, 220, 225, 230, 235 and 240 minutes) and value of basal (mean of values measured at 90, 95, 100, 105, 110, 115 and 120 minutes).
Secondarysystolic blood pressure and diastolic blood pressure240 minutes
Secondaryheart rate240 minutes
SecondaryMeasure of QTc interval with electrocardiogram examination240 minutes
SecondaryClinic sign of apelin intolerance240 minutes
SecondaryDosage of plasma proteins240 minutesA kinetic is realized with samples at 0, 15, 30, 45, 60, 75, 90, 100, 110, 120, 135, 150, 165, 180, 195, 200, 220, 230 and 240 minutes
SecondaryClinic sign of apelin allergy240 minutesModification in physiological parameters
SecondaryClinic sign of apelin toxicity240 minutesModification in physiological parameters

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers1

The papers the trial lists on ClinicalTrials.gov.

PMIDListed as
28681996RESULT

Source PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT02724566

GET https://conductscience.org/api/trials/v1/NCT02724566/registered