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Trial · NCT02737501

Results by group29

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Progression-free Survival (PFS)Randomized Phase: Brigatinib 90 mg QD/180 QD24.01695% Confidence Interval 18.46 to 43.20months
Progression-free Survival (PFS)Randomized Phase: Crizotinib 250 mg BID11.07295% Confidence Interval 9.13 to 13.01months
Progression-free Survival (PFS)Crossover Phase: Brigatinib 90 mg QD/180 mg QD16.82195% Confidence Interval 10.12 to 23.85months
Confirmed Objective Response Rate (ORR)Randomized Phase: Brigatinib 90 mg QD/180 QD74.595% Confidence Interval 66.30 to 81.52percentage of participants
Confirmed Objective Response Rate (ORR)Randomized Phase: Crizotinib 250 mg BID62.395% Confidence Interval 53.68 to 70.42percentage of participants
Confirmed Objective Response Rate (ORR)Crossover Phase: Brigatinib 90 mg QD/180 mg QD56.995% Confidence Interval 44.04 to 69.15percentage of participants
Confirmed Intracranial ORR (iORR)Randomized Phase: Brigatinib 90 mg QD/180 QD66.095% Confidence Interval 50.69 to 79.14percentage of participants
Confirmed Intracranial ORR (iORR)Randomized Phase: Crizotinib 250 mg BID14.395% Confidence Interval 5.94 to 27.24percentage of participants
Confirmed Intracranial ORR (iORR)Crossover Phase: Brigatinib 90 mg QD/180 mg QD35.795% Confidence Interval 21.55 to 51.97percentage of participants
Intracranial Progression Free SurvivalRandomized Phase: Brigatinib 90 mg QD/180 QD23.95195% Confidence Interval 12.91 to 30.78months
Intracranial Progression Free SurvivalRandomized Phase: Crizotinib 250 mg BID5.52095% Confidence Interval 3.71 to 7.52months
Intracranial Progression Free SurvivalCrossover Phase: Brigatinib 90 mg QD/180 mg QD24.54295% Confidence Interval 12.58 to NAmonths
Overall Survival (OS)Randomized Phase: Brigatinib 90 mg QD/180 QDNA95% Confidence Interval NA to NAmonths
Overall Survival (OS)Randomized Phase: Crizotinib 250 mg BIDNA95% Confidence Interval NA to NAmonths
Overall Survival (OS)Crossover Phase: Brigatinib 90 mg QD/180 mg QD35.02395% Confidence Interval 30.42 to NAmonths
Duration of Response (DOR)Randomized Phase: Brigatinib 90 mg QD/180 QD33.150Full Range 1.84 to 50.60months
Duration of Response (DOR)Randomized Phase: Crizotinib 250 mg BID13.832Full Range 1.45 to 49.81months
Duration of Response (DOR)Crossover Phase: Brigatinib 90 mg QD/180 mg QD19.154Full Range 1.97 to 33.15months
Time to Response (TTR)Randomized Phase: Brigatinib 90 mg QD/180 QD1.840Full Range 1.02 to 29.47months
Time to Response (TTR)Randomized Phase: Crizotinib 250 mg BID1.873Full Range 0.79 to 7.43months

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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