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Trial · NCT02738801

Results by group22

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Number of Patients With Treatment-Emergent Adverse Events (AEs)Placebo QD4Participants
Number of Patients With Treatment-Emergent Adverse Events (AEs)GLPG1690 600 mg QD11Participants
Mean Maximum Observed Plasma Concentration (Cmax; Micrograms Per Milliliter [µg/mL]) of GLPG1690GLPG1690 600 mg QD6.06Standard Deviation 4.92µg/mL
Median Time to Occurrence of GLPG1690 Cmax (Tmax; Hours [h])GLPG1690 600 mg QD4Full Range 1.5 to 6hours
Mean Area Under the Plasma Concentration-Time Curve (AUC[t]; µg.h/mL) of GLPG1690GLPG1690 600 mg QD55.6Standard Deviation 46.6µg.h/mL
Mean GLPG1690 Plasma Concentration Observed at Predose (Ctrough; µg/mL)GLPG1690 600 mg QD0.624Standard Deviation 0.846µg/mL
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodPlacebo QDBaseline0.4180Standard Error 0.1088peak area ratio
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodGLPG1690 600 mg QDBaseline0.3311Standard Error 0.0670peak area ratio
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodPlacebo QDDay 280.3650Standard Error 0.0895peak area ratio
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodGLPG1690 600 mg QDDay 280.1476Standard Error 0.0380peak area ratio
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodPlacebo QDDay 28 (1.5 hours postdose)0.4071Standard Error 0.1352peak area ratio
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodGLPG1690 600 mg QDDay 28 (1.5 hours postdose)0.0479Standard Error 0.0120peak area ratio
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodPlacebo QDDay 28 (6 hours postodse)0.3402Standard Error 0.1373peak area ratio
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodGLPG1690 600 mg QDDay 28 (6 hours postodse)0.0314Standard Error 0.0046peak area ratio
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodPlacebo QDDay 840.4080Standard Error 0.1090peak area ratio
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodGLPG1690 600 mg QDDay 840.0898Standard Error 0.0160peak area ratio
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodPlacebo QDDay 980.4672Standard Error 0.1647peak area ratio
Mean Peak Area Ratio of Lysophosphatidic Acid (LPA) C18:2 Species in BloodGLPG1690 600 mg QDDay 980.5172Standard Error 0.1660peak area ratio
Mean Peak Area Ratio of LPA C18:2 Species in Bronchoalveolar Lavage Fluid (BALF)Placebo QDBaseline0.0026Standard Error 0.0011peak area ratio
Mean Peak Area Ratio of LPA C18:2 Species in Bronchoalveolar Lavage Fluid (BALF)GLPG1690 600 mg QDBaseline0.0009Standard Error 0.0002peak area ratio

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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