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Trial · NCT02740179

Registered outcomes16

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryMyocardial Perfusion by PET12 Months
Change (value at 12 months minus value at baseline) in myocardial perfusion assessed by coronary flow reserve measured via cardiac positron emission tomography. Coronary flow reserve is given by the ratio of blood flow at stress during maximal dilation of the coronary arteries to blood flow at rest.
PrimaryMyocardial Perfusion by MRI12 MonthsChange (value at 12 months minus value at baseline) in myocardial perfusion assessed by myocardial blood flow measured via cardiac magnetic resonance imaging
PrimaryMyocardial Inflammation12 Months
Change (value at 12 months minus value at baseline) in myocardial inflammation measured by extracellular mass index (a measure of the inflammation within the heart) via cardiac magnetic resonance imaging
SecondaryCoronary Plaque12 Months
Change (value at 12 months minus value at baseline) in coronary plaque measured via coronary computed tomography angiogram assessed by coronary calcium score Scale: minimum 0 to maximum no limit, higher score indicates more plaque
SecondaryMarkers of Vascular Dysfunction12 MonthsChange (value at 12 months minus value at baseline) in serum hs-cTnT
SecondaryMarkers of Systemic Inflammation hsIL-612 MonthsChange (value at 12 months minus value at baseline) in plasma hsIL-6
SecondaryMarkers of Systemic Inflammation hsCRP12 MonthsChange (value at 12 months minus value at baseline) in plasma hsCRP
SecondaryMarkers of Immune Activation MCP-112 MonthsChange (value at 12 months minus value at baseline) in plasma MCP-1
SecondaryMarkers of Immune Activation sCD16312 MonthsChange (value at 12 months minus value at baseline) in plasma sCD163
SecondaryMarkers of Subclinical Injury12 MonthsChange (value at 12 months minus value at baseline) in serum NT-proBNP
SecondaryMarkers of Fibrosis12 MonthsChange (value at 12 months minus value at baseline) in myocardial fibrosis measured by T1 (a signal intensity that measures fibrosis) via cardiac magnetic resonance imaging
SecondaryArterial Inflammation12 Months
Percentage change (value at 12 months minus value at baseline) in target to background ratio (a measure of arterial inflammation) of the index vessel measured via positron emission tomography/computed tomography
SecondaryMarkers of Arterial Inflammation12 MonthsChange (value at 12 months minus value at baseline) in plasma LpPLA2
SecondaryAssessment of Cardiac Structure by Left Ventricular Mass on Cardiac Imaging12 MonthsChange (value at 12 months minus value at baseline) in left ventricular mass on cardiac magnetic resonance imaging
SecondaryAssessment of Cardiac Systolic Function Via Cardiac Imaging12 MonthsChange (value at 12 months minus value at baseline) in global circumferential strain (GCS) on cardiac magnetic resonance imaging
SecondaryAssessment of Cardiac Diastolic Function Via Cardiac Imaging12 MonthsChange (value at 12 months minus value at baseline) in left ventricular end diastolic volume on cardiac magnetic resonance imaging

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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