Neurostimulation and Cognitive Intervention in Alzheimer's Disease
NCT02772185, Phase 2, Phase 3, Unknown, Federal University of Paraíba
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Neurostimulation and Cognitive Intervention in Alzheimer's Disease | ClinicalTrials.gov |
| NCT number | NCT02772185 | ClinicalTrials.gov |
| Status | Unknown | ClinicalTrials.gov |
| Phases | Phase 2, Phase 3 | ClinicalTrials.gov |
| Enrollment | 60 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Federal University of Paraíba | ClinicalTrials.gov |
| Conditions | Alzheimer's Disease | ClinicalTrials.gov |
| Interventions | active tDCS, sham tDCS, real CT, placebo CT | ClinicalTrials.gov |
| First posted | 2016-05-13 | ClinicalTrials.gov |
| Last updated | 2016-05-13 | ClinicalTrials.gov |
Registered outcomes 13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change in cognitive function assessed on the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-Cog) | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Change in cognitive ability assessed on the Wechsler Adult Intelligence Scale | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Change in visuo-spatial working memory assessed on the Corsi block task | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Change in verbal working memory assessed on the Digit Span task | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Change in speed of cognitive processing and executive functioning assessed on the Trail Making Test | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Change in executive function assessed on the Stroop Color and Word Test | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Change in verbal fluency assessed on the FAS Verbal Fluency Test | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Change in functional ability assessed on the Disability Assessment Dementia | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Change in visual recognition assessed on the Poppelreuter-Ghent's Overlapping Figures test | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Change in behavioral and psychological disturbances assessed on the Neuropsychiatric Inventory Questionnaire | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Change in subjective burden among caregivers assessed on the Zarit Burden Interview | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Change in electrical activity of the brain assessed on the Electroencephalogram (EEG) | Baseline (week 1), Endpoint (week 8) and Follow up (assessed up to 12 months) | ClinicalTrials.gov | |
| Secondary | Side Effects Questionnaire | From date of first neurostimulation until the date of last neurostimulation, assessed up to 12 months | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 4
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 7
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Corsi Block-Tapping Test | Secondary outcome | ConductCognition |
| Digit Span Test | Secondary outcome | ConductCognition |
| Overlapping Outlines Task | Secondary outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Trail Making Test A | Secondary outcome | ConductCognition |
| Trail Making Test B | Secondary outcome | ConductCognition |
| Verbal Fluency | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)