Trial · NCT02775864
Comparative Effectiveness of Adaptive Treatment Strategies for Schizophrenia
NCT02775864, Completed, New York State Psychiatric Institute; results first posted 2019-06-07
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparative Effectiveness of Adaptive Treatment Strategies for Schizophrenia. Trials, record NCT02775864. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02775864
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparative Effectiveness of Adaptive Treatment Strategies for Schizophrenia
- NCT number
- NCT02775864
- Status
- Completed
- Enrollment
- 81,921 participants, actual
- Lead sponsor
- New York State Psychiatric Institute
- Conditions
- Schizophrenia, Schizoaffective Disorder
- Interventions
- Antipsychotic, Antidepressant, Benzodiazepine, Mood stabilizer
- First posted
- 2016-05-18
- Last updated
- 2024-05-01
- Results first posted
- 2019-06-07
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Psychiatric Hospitalization | One year | Number of participants hospitalized for a mental health reason |
| Secondary | Emergency Department Visit for Mental Health Reason | One year | Number of Participants with an Emergency Department visit for mental health reason |
| Secondary | Death | One year | Participants who died |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Psychiatric Hospitalization | One year | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Emergency Department Visit for Mental Health Reason | One year | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Death | One year | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group12
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Psychiatric Hospitalization | Antipsychotic | 4965 | Participants | ||
| Psychiatric Hospitalization | Antidepressant | 5247 | Participants | ||
| Psychiatric Hospitalization | Benzodiazepine | 2385 | Participants | ||
| Psychiatric Hospitalization | Mood Stabilizer | 3093 | Participants | ||
| Emergency Department Visit for Mental Health Reason | Antipsychotic | 5505 | Participants | ||
| Emergency Department Visit for Mental Health Reason | Antidepressant | 6508 | Participants | ||
| Emergency Department Visit for Mental Health Reason | Benzodiazepine | 2930 | Participants | ||
| Emergency Department Visit for Mental Health Reason | Mood Stabilizer | 3429 | Participants | ||
| Death | Antipsychotic | 259 | Participants | ||
| Death | Antidepressant | 327 | Participants |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 results by groupParticipant flow12
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Antipsychotic | 26,014 | |
| Overall Study | STARTED | Antidepressant | 31,117 | |
| Overall Study | STARTED | Benzodiazepine | 11,941 | |
| Overall Study | STARTED | Mood Stabilizer | 12,849 | |
| Overall Study | COMPLETED | Antipsychotic | 22,772 | |
| Overall Study | COMPLETED | Antidepressant | 26,218 | |
| Overall Study | COMPLETED | Benzodiazepine | 10,081 | |
| Overall Study | COMPLETED | Mood Stabilizer | 10,765 | |
| Overall Study | NOT COMPLETED | Antipsychotic | 3,242 | |
| Overall Study | NOT COMPLETED | Antidepressant | 4,899 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 participant flowAdverse events8
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Incident cases of diabetes mellitus | Endocrine disorders | Antipsychotic | 967 | 21,738 | 967 |
| other | Incident cases of diabetes mellitus | Endocrine disorders | Antidepressant | 1,004 | 26,062 | 1,004 |
| other | Incident cases of diabetes mellitus | Endocrine disorders | Benzodiazepine | 424 | 9,764 | 424 |
| other | Incident cases of diabetes mellitus | Endocrine disorders | Mood Stabilizer | 423 | 10,564 | 423 |
| serious | Admission for Cardiovascular Disease | Cardiac disorders | Antipsychotic | 67 | 26,014 | |
| serious | Admission for Cardiovascular Disease | Cardiac disorders | Antidepressant | 102 | 31,117 | |
| serious | Admission for Cardiovascular Disease | Cardiac disorders | Benzodiazepine | 43 | 11,941 | |
| serious | Admission for Cardiovascular Disease | Cardiac disorders | Mood Stabilizer | 41 | 12,849 |
Source ClinicalTrials.gov
Adverse event totals12
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Antipsychotic | 259 | 26,014 |
| Total, all-cause mortality | Antidepressant | 327 | 31,117 |
| Total, all-cause mortality | Benzodiazepine | 204 | 11,941 |
| Total, all-cause mortality | Mood Stabilizer | 161 | 12,849 |
| Total, other adverse events | Antipsychotic | 967 | 21,738 |
| Total, other adverse events | Antidepressant | 1,004 | 26,062 |
| Total, other adverse events | Benzodiazepine | 424 | 9,764 |
| Total, other adverse events | Mood Stabilizer | 423 | 10,564 |
| Total, serious adverse events | Antipsychotic | 67 | 26,014 |
| Total, serious adverse events | Antidepressant | 102 | 31,117 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 adverse event totalsPapers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02775864
GET https://conductscience.org/api/trials/v1/NCT02775864/registered