Trial · NCT02778906
Abatacept Reversing Subclinical Inflammation as Measured by MRI in ACPA Positive Arthralgia
NCT02778906, Phase 3, Completed, University of Erlangen-Nürnberg Medical School
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Abatacept Reversing Subclinical Inflammation as Measured by MRI in ACPA Positive Arthralgia. Trials, record NCT02778906. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02778906
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Abatacept Reversing Subclinical Inflammation as Measured by MRI in ACPA Positive Arthralgia
- NCT number
- NCT02778906
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 98 participants, actual
- Lead sponsor
- University of Erlangen-Nürnberg Medical School
- Conditions
- Arthralgia, Arthritis
- Interventions
- Abatacept, Placebo
- First posted
- 2016-05-20
- Last updated
- 2020-03-10
Source ClinicalTrials.gov
Registered outcomes26
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Proportion of patients with an improvement of acute inflammation characterised as improvement of synovitis (synovialitis or tenosynovitis) or osteitis in the MRI of the dominant hand after 6 months of treatment with abatacept or placebo | 6 months | |
| Secondary | RAMRIS synovitis score in the dominant hand 12 and 18 months. | 6,12,18 months | |
| Secondary | Tenosynovitis score in the dominant hand. | 6,12,18 months | |
| Secondary | Proportion of patients with new or persistent arthralgia. | 6,12,18 months | |
| Secondary | Time to disappearance of arthralgia. | 6 months | |
| Secondary | Proportion of patients with clinical arthritis defined by joint swelling | 6,12,18 months | |
| Secondary | Proportion of patients with RA (ACR/EULAR 2010 criteria) | 6,12,18 months | |
| Secondary | Proportion of patients with radiological progress in HR-pQCT analysis comparing baseline image with end of study image. | 18 months | |
| Secondary | Tender Joint Count 68 | 3,6,9,12,15 and 18 months | |
| Secondary | Disease activity score (DAS) 28 | 3,6,9,12,15 and 18 months |
1 to 10 of 26Source ClinicalTrials.gov
See all 26 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02778906
GET https://conductscience.org/api/trials/v1/NCT02778906/registered?page=2