Chronic Obstructive Pulmonary Disorder and Acute Exercise
NCT02780219, Not applicable, Completed, Texas A&M University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Chronic Obstructive Pulmonary Disorder and Acute Exercise | ClinicalTrials.gov |
| NCT number | NCT02780219 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 57 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Texas A&M University | ClinicalTrials.gov |
| Conditions | Pulmonary Disease, Chronic Obstructive | ClinicalTrials.gov |
| Interventions | stable amino acid infusion, acute exercise with amino acid infusion, 24-hour post exercise amino acid infusion | ClinicalTrials.gov |
| First posted | 2016-05-23 | ClinicalTrials.gov |
| Last updated | 2025-02-03 | ClinicalTrials.gov |
Registered outcomes 15
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change in net whole-body protein synthesis | 2, 5, 10, 15, 20, 30, 40, 50, 60, 90, 120, 150, 180, 210 and 240 ± 5 minutes | Change in whole-body protein synthesis rate | ClinicalTrials.gov |
| Secondary | glutamate related metabolism | 2, 5, 10, 15, 20, 30, 40, 50, 60, 90, 120, 150, 180, 210 and 240 ± 5 minutes | ClinicalTrials.gov | |
| Secondary | tryptophan related metabolism | 2, 5, 10, 15, 20, 30, 40, 50, 60, 90, 120, 150, 180, 210 and 240 ± 5 minutes | ClinicalTrials.gov | |
| Secondary | arginine related metabolism | 2, 5, 10, 15, 20, 30, 40, 50, 60, 90, 120, 150, 180, 210 and 240 ± 5 minutes | ClinicalTrials.gov | |
| Secondary | leucine related metabolism | 2, 5, 10, 15, 20, 30, 40, 50, 60, 90, 120, 150, 180, 210 and 240 ± 5 minutes | ClinicalTrials.gov | |
| Secondary | taurine related metabolism | 2, 5, 10, 15, 20, 30, 40, 50, 60, 90, 120, 150, 180, 210 and 240 ± 5 minutes | ClinicalTrials.gov | |
| Secondary | Body Composition | 15 minutes on screening or study day 1 | Body composition as measured by Dual-Energy X-ray Absorptiometry | ClinicalTrials.gov |
| Secondary | changes in skeletal muscle fatigue | on study day 1 and change from day 2 and day 3 | kin-com 1-leg test | ClinicalTrials.gov |
| Secondary | Group differences in state of mood as measured by the Hospital Anxiety and Depression Scale (HADS) | 1 day | a fourteen item self-assessment scale. Seven of the items related to anxiety and seven relate to depression. Each item on the questionnaire is scored from 0-3 and this means that a person can score between 0 (no symptoms) and 21 (severe symptoms) for either anxiety or depression. | ClinicalTrials.gov |
| Secondary | Group differences in attention and executive functions as measured by Stroop Color-Word Test (SCWT) | on study day 1 and change from day 2 and day 3 | a word page with words printed in black ink, a color page with blocks printed in color, and a color-word page where the color and the word do not match. The examinee reads the words or names the ink colors as quickly as possible within a time limit. Measures selective attention and inhibitory control. The total time in seconds was reported for each trial. | ClinicalTrials.gov |
| Secondary | Group differences in learning and memory as measured by Digit Span | on study day 1 and change from day 2 and day 3 | recall of numbers in the same order (Digit Forward) and in reverse order (Digit Backward). Measures auditory attention and verbal working memory. | ClinicalTrials.gov |
| Secondary | Group differences in attention and executive functions as measured by Digit Symbol Modalities Test | on study day 1 and change from day 2 and day 3 | Using a legend with nine symbols that correspond to nine different numbers, the examinee is asked to fill in as many blank squares as possible by copying the corresponding number in each box, indexed by a symbol within a 90 sec time limit. | ClinicalTrials.gov |
| Secondary | Group differences in activity as measured by Physical Activity Scale for the Elderly (PASE) | study day 1 | This questionnaire is intended for use in an elderly population and focuses on 3 types of activities: leisure time activities, household activities and work-related activities. | ClinicalTrials.gov |
| Secondary | 24 hour diet recall | study day 1 | The subject is asked to recall in detail all the food and drink consumed during the 24 hours prior to the test day. | ClinicalTrials.gov |
| Secondary | appetite questionnaire | study day 1 | The subject is asked to rate various aspects of their appetite as relates to overall health | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 7
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Digit Span Test | Secondary outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)