Trial · NCT02789592
Efficacy and Safety of Melatonin PR and Clonazepam in Patients With REM Sleep Behavior Disorder in Parkinson Disease
NCT02789592, Phase 2, Unknown, Seoul National University Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy and Safety of Melatonin PR and Clonazepam in Patients With REM Sleep Behavior Disorder in Parkinson Disease. Trials, record NCT02789592. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02789592
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy and Safety of Melatonin PR and Clonazepam in Patients With REM Sleep Behavior Disorder in Parkinson Disease
- NCT number
- NCT02789592
- Status
- Unknown
- Phases
- Phase 2
- Enrollment
- 30 participants, estimated
- Lead sponsor
- Seoul National University Hospital
- Conditions
- REM Sleep Behavior Disorder, Parkinson Disease
- Interventions
- Melatonin PR, Clonazepam, Melatonin PR placebo, Clonazepam placebo
- First posted
- 2016-06-03
- Last updated
- 2016-06-03
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Clinical Global Impression-Improvement scale (CGI-I) | Four weeks (plus or minus 3 days) | Clinician assessed rating scale of clinical improvement or worsening relative to a baseline state, scored as 1, very much improved; 2, much improved; 3, minimally improved; 4, no change; 5, minimally worse; 6, much worse; or 7, very much worse. |
| Secondary | Mean change of the Clinical Global Impression-Severity scale (CGI-S) | Four weeks (plus or minus 3 days) | |
| Secondary | Patient Global Impression-Improvement scale (PGI-I) | Four weeks (plus or minus 3 days) | |
| Secondary | Mean change of the Patient Global Impression-Severity scale (PGI-S) | Four weeks (plus or minus 3 days) | |
| Secondary | modified RBD Questionnaire-HongKong (mRBDQ-HK) | Four weeks (plus or minus 3 days) | |
| Secondary | Mean change of the Epworth Sleepiness Scale (ESS) | Four weeks (plus or minus 3 days) | |
| Secondary | Mean change of the Parkinson Disease Sleep Scale (PDSS) | Four weeks (plus or minus 3 days) | |
| Secondary | Mean change of the Montreal Cognitive Assessment (MoCA) | Four weeks (plus or minus 3 days) | |
| Secondary | Mean change of the Unified Parkinson's Disease Rating Scale (UPDRS) | Four weeks (plus or minus 3 days) | |
| Secondary | Sleep diary | Four weeks (plus or minus 3 days) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02789592
GET https://conductscience.org/api/trials/v1/NCT02789592/registered