Trial · NCT02808533
Topiramate and Schizophrenia: Effects on Weight and Psychopathology
NCT02808533, Not applicable, Active not recruiting, Centre for Addiction and Mental Health
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Topiramate and Schizophrenia: Effects on Weight and Psychopathology. Trials, record NCT02808533. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02808533
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Topiramate and Schizophrenia: Effects on Weight and Psychopathology
- NCT number
- NCT02808533
- Status
- Active not recruiting
- Phases
- Not applicable
- Enrollment
- 50 participants, estimated
- Lead sponsor
- Centre for Addiction and Mental Health
- Conditions
- Schizophrenia, Schizoaffective Disorder
- Interventions
- Topiramate, Placebo
- First posted
- 2016-06-21
- Last updated
- 2026-05-28
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Weight loss | 16 weeks | Measured in pounds |
| Secondary | Insulin sensitivity | 16 weeks | Measured through Oral Glucose Tolerance Test (pmol/L) |
| Secondary | Psychopathology - Positive and Negative Syndrome Scale (PANSS) | 16 weeks | Anchored scale to rate positive and negative psychiatric symptoms |
| Secondary | Glucose Tolerance | 16 weeks | Measured through Oral Glucose Tolerance Test (mmol/L) |
| Secondary | Psychopathology - Brief Psychiatric Rating Scale (BPRS) | 16 weeks | Anchored rating scale for psychiatric symptoms |
| Secondary | Psychopathology - Clinical Global Impression (CGI) | 16 weeks | Anchored scale to rate global impression of patient |
| Secondary | Psychopathology - Global Assessment of Functioning (GAF) | 16 weeks | Anchored scale to rate global functioning of patient |
| Other | Visceral adiposity changes | Baseline and 16 weeks | Measured through MRI |
| Other | Cognition - Brief Assessment of Cognition in Schizophrenia (BACS) | 16 weeks | A standardized assessment of cognitive in patients with schizophrenia |
| Other | Volumetric Brain changes | Baseline and 16 weeks | Measured through MRI |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02808533
GET https://conductscience.org/api/trials/v1/NCT02808533/registered