Trial · NCT02834624
Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress Syndrome
NCT02834624, Not applicable, Completed, University of Missouri-Columbia; results first posted 2017-06-06
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress Syndrome. Trials, record NCT02834624. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02834624
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress Syndrome
- NCT number
- NCT02834624
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 30 participants, actual
- Lead sponsor
- University of Missouri-Columbia
- Conditions
- Respiratory Distress Syndrome
- Interventions
- Poractant alfa, calfactant
- First posted
- 2016-07-15
- Last updated
- 2017-06-06
- Results first posted
- 2017-06-06
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change From Baseline in Blood C-reactive (CRP) Protein | baseline, 48 hours | Difference between measurement of CRP at baseline and 48 hours after administration of surfactant |
| Secondary | Presence of Pulmonary Hemorrhage | intraoperative | Significant and Persistent Blood present in the trachea during endotracheal tube suctioning. |
| Secondary | Change in Number of Tracheal Macrophages | baseline, 48 hours | measurement of lipid peroxidation in tracheal aspirate samples and cytology of tracheal aspirates.in tracheal aspirate |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change From Baseline in Blood C-reactive (CRP) Protein | baseline, 48 hours | mg/dL | MEAN | |
| SECONDARY | Presence of Pulmonary Hemorrhage | intraoperative | This data is unavailable from the research department as it was not collected. | ||
| SECONDARY | Change in Number of Tracheal Macrophages | baseline, 48 hours | white cells/high-powered field | MEAN |
Source ClinicalTrials.gov
Results by group4
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change From Baseline in Blood C-reactive (CRP) Protein | Poractant | 1.300 | Standard Deviation 1.644 | mg/dL | |
| Change From Baseline in Blood C-reactive (CRP) Protein | Calfactant | 0.193 | Standard Deviation 0.337 | mg/dL | |
| Change in Number of Tracheal Macrophages | Poractant | 2.3 | Standard Deviation 1.8 | white cells/high-powered field | |
| Change in Number of Tracheal Macrophages | Calfactant | 2.0 | Standard Deviation 1.2 | white cells/high-powered field |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Poractant | 15 | |
| Overall Study | STARTED | Calfactant | 15 | |
| Overall Study | COMPLETED | Poractant | 15 | |
| Overall Study | COMPLETED | Calfactant | 15 | |
| Overall Study | NOT COMPLETED | Poractant | 0 | |
| Overall Study | NOT COMPLETED | Calfactant | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Calfactant | 0 | 15 |
| Total, all-cause mortality | Poractant Alfa | 0 | 15 |
| Total, other adverse events | Calfactant | 0 | 15 |
| Total, other adverse events | Poractant Alfa | 0 | 15 |
| Total, serious adverse events | Calfactant | 0 | 15 |
| Total, serious adverse events | Poractant Alfa | 0 | 15 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Calfactant vs Poractant Alfa: deaths from any cause | Trial comparisons |
| Calfactant vs Poractant Alfa: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02834624
GET https://conductscience.org/api/trials/v1/NCT02834624/registered