Trial · NCT02835339
Magnesium Sulfate in Obese Preeclamptics
NCT02835339, Phase 4, Completed, Oregon Health and Science University; results first posted 2020-05-13
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Magnesium Sulfate in Obese Preeclamptics. Trials, record NCT02835339. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02835339
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Magnesium Sulfate in Obese Preeclamptics
- NCT number
- NCT02835339
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 66 participants, actual
- Lead sponsor
- Oregon Health and Science University
- Conditions
- Preeclampsia
- Interventions
- Magnesium sulfate 4g loading dose, 1g/hr infusion, Magnesium sulfate 6g loading dose, 2g/hr infusion
- First posted
- 2016-07-18
- Last updated
- 2020-05-13
- Results first posted
- 2020-05-13
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Maternal Serum Magnesium Level at 4 Hours After Administration | 4 hours | magnesium level in mg/dL |
| Secondary | Maternal Serum Magnesium Level at Time of Delivery | Within 20 minutes of delivery | magnesium level in mg/dL |
| Secondary | Maternal Side Effects | 4 hours | Presence or absence of the following: flushing, lethargy, palpitations, pain at IV site, respiratory depression |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Maternal Serum Magnesium Level at 4 Hours After Administration | 4 hours | mg/dL | MEAN | |
| SECONDARY | Maternal Serum Magnesium Level at Time of Delivery | Within 20 minutes of delivery | mg/dL | MEAN | |
| SECONDARY | Maternal Side Effects | 4 hours | percentage of participants | NUMBER |
Source ClinicalTrials.gov
Results by group16
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Maternal Serum Magnesium Level at 4 Hours After Administration | MgSO4 4g Load, 1g/hr Infusion | 3.53 | Standard Deviation .3 | mg/dL | |
| Maternal Serum Magnesium Level at 4 Hours After Administration | MgSO4 6g Load, 2g/hr Infusion | 4.41 | Standard Deviation .5 | mg/dL | |
| Maternal Serum Magnesium Level at Time of Delivery | MgSO4 4g Load, 1g/hr Infusion | 3.73 | Standard Deviation 0.7 | mg/dL | |
| Maternal Serum Magnesium Level at Time of Delivery | MgSO4 6g Load, 2g/hr Infusion | 5.44 | Standard Deviation 1.0 | mg/dL | |
| Maternal Side Effects | MgSO4 4g Load, 1g/hr Infusion | Nausea | 5.5 | percentage of participants | |
| Maternal Side Effects | MgSO4 6g Load, 2g/hr Infusion | Nausea | 10.5 | percentage of participants | |
| Maternal Side Effects | MgSO4 4g Load, 1g/hr Infusion | Flushing | 0 | percentage of participants | |
| Maternal Side Effects | MgSO4 6g Load, 2g/hr Infusion | Flushing | 5.2 | percentage of participants | |
| Maternal Side Effects | MgSO4 4g Load, 1g/hr Infusion | Lethargy | 0 | percentage of participants | |
| Maternal Side Effects | MgSO4 6g Load, 2g/hr Infusion | Lethargy | 0 | percentage of participants |
1 to 10 of 16Source ClinicalTrials.gov
See all 16 results by groupParticipant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | MgSO4 4g Load, 1g/hr Infusion | 31 | |
| Overall Study | STARTED | MgSO4 6g Load, 2g/hr Infusion | 35 | |
| Overall Study | COMPLETED | MgSO4 4g Load, 1g/hr Infusion | 18 | |
| Overall Study | COMPLETED | MgSO4 6g Load, 2g/hr Infusion | 19 | |
| Overall Study | NOT COMPLETED | MgSO4 4g Load, 1g/hr Infusion | 13 | |
| Overall Study | NOT COMPLETED | MgSO4 6g Load, 2g/hr Infusion | 16 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | MgSO4 4g Load, 1g/hr Infusion | 0 | 18 |
| Total, all-cause mortality | MgSO4 6g Load, 2g/hr Infusion | 0 | 19 |
| Total, other adverse events | MgSO4 4g Load, 1g/hr Infusion | 0 | 18 |
| Total, other adverse events | MgSO4 6g Load, 2g/hr Infusion | 0 | 19 |
| Total, serious adverse events | MgSO4 4g Load, 1g/hr Infusion | 0 | 18 |
| Total, serious adverse events | MgSO4 6g Load, 2g/hr Infusion | 0 | 19 |
Source ClinicalTrials.gov
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| MgSO4 4g Load, 1g/hr Infusion vs MgSO4 6g Load, 2g/hr Infusion: deaths from any cause | Trial comparisons |
| MgSO4 4g Load, 1g/hr Infusion vs MgSO4 6g Load, 2g/hr Infusion: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02835339
GET https://conductscience.org/api/trials/v1/NCT02835339/registered