Registered outcomes15

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

1 to 15 of 15

List	Outcome	Time frame	Description
Primary	Safety assessed by development of RLT, AEs and laboratory parameters of indoximod.	6 months	Phase 1
Primary	Comparison of serum concentrations (Cmax/Steady State) of indoximod freebase and indoximod salt formulation.	6 months	Phase 1
Secondary	Measurable Residual Disease Rate	2 years
Secondary	Clinical response rate	2 years
Secondary	Duration of complete response	2 years
Secondary	Event free survival	2 years	Time on study to induction failure, relapse or death
Secondary	Cumulative incidence of relapse (CIR)	2 years
Secondary	Overall survival (OS)	2 years
Secondary	Proportion of AML patients who become eligible for bone marrow transplantation	2 years
Secondary	Frequency and severity of adverse events	2 years
Secondary	Pharmacokinetics: Serum concentrations (Cmax/Steady State)	6 months	Characterize the pharmacokinetics (PK) of indoximod, idarubicin and cytarabine through analysis of blood samples
Other	Serum kynurenine and tryptophan levels	2 years	Characterize the pharmacodynamic (PD) effect of indoximod
Other	IDO expression by immunohistochemistry in diagnostic and follow-up bone marrow biopsy specimens	2 years
Other	IDO protein and mRNA expression in diagnostic and follow-up bone marrow aspirate samples	2 years
Other	Methylation status of the IDO promoter in diagnostic and follow up bone marrow aspiration samples	2 years

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/trials/v1/NCT02835729/registered