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Trial · NCT02842242

Results by group18

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change in Post-exercise Peak LVOT Gradient From Baseline to Week 12Cohort A-89.595% Confidence Interval -138.3 to -40.7mm Hg
Change in Post-exercise Peak LVOT Gradient From Baseline to Week 12Cohort B-25.095% Confidence Interval -47.1 to -3.0mm Hg
Number of Participants Achieving a Post-exercise Peak LVOT Gradient Response of < 30 mmHg. Gradient < 30 mmHgCohort A8Participants
Number of Participants Achieving a Post-exercise Peak LVOT Gradient Response of < 30 mmHg. Gradient < 30 mmHgCohort B0Participants
Change in Dyspnea Symptom Score From Baseline to Week 12Cohort A-3.195% Confidence Interval -4.1 to -2.1units on a scale
Change in Dyspnea Symptom Score From Baseline to Week 12Cohort B-3.095% Confidence Interval -5.0 to -1.0units on a scale
Change in Peak VO2 From Baseline to Week 12Cohort A3.595% Confidence Interval 1.2 to 5.9mL/kg/min
Change in Peak VO2 From Baseline to Week 12Cohort B1.795% Confidence Interval 0.03 to 3.3mL/kg/min
Change in VE/VCO2 From Baseline to Week 12Cohort A-2.295% Confidence Interval -6.1 to 1.7Ratio
Change in VE/VCO2 From Baseline to Week 12Cohort B-2.595% Confidence Interval -4.3 to -0.7Ratio
Change in Resting LVEF From Baseline to Week 12Cohort A-14.695% Confidence Interval -23.1 to -6.2Percent change
Change in Resting LVEF From Baseline to Week 12Cohort B-5.595% Confidence Interval -9.8 to -1.2Percent change
Change in LV Fractional Shortening (LVFS) From Baseline to Week 12Cohort A-18.60Standard Deviation 13.05Percent
Change in LV Fractional Shortening (LVFS) From Baseline to Week 12Cohort B-3.98Standard Deviation 11.42Percent
Change in Global Longitudinal Strain (GLS) From Baseline to Week 12Cohort A0.56Standard Deviation 3.778Percent
Change in Global Longitudinal Strain (GLS) From Baseline to Week 12Cohort B0.18Standard Deviation 2.806Percent
Change in Post-exercise Peak LVOT Gradient From Week 12 to Week 16Cohort A55.22Standard Deviation 40.84mm Hg
Change in Post-exercise Peak LVOT Gradient From Week 12 to Week 16Cohort B84.08Standard Deviation 28.38mm Hg

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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