Trial · NCT02847494
Corticosteroids for Acute Migraine in the Emergency Department
NCT02847494, Phase 4, Completed, Montefiore Medical Center; results first posted 2019-01-08
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Corticosteroids for Acute Migraine in the Emergency Department. Trials, record NCT02847494. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02847494
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Corticosteroids for Acute Migraine in the Emergency Department
- NCT number
- NCT02847494
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 220 participants, actual
- Lead sponsor
- Montefiore Medical Center
- Conditions
- Migraine
- Interventions
- metoclopramide, Dexamethasone, methylprednisolone acetate
- First posted
- 2016-07-28
- Last updated
- 2019-01-08
- Results first posted
- 2019-01-08
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Headache Days as Self-reported by Participants | 7 days after discharge from emergency department | At the seven day follow-up, participants will be asked by phone how many days they experienced headaches since being discharged. |
| Secondary | Number of Participants With Sustained Headache Freedom | 7 days after discharge from emergency department | Sustained headache freedom is defined as achieving a headache intensity = none within two hours of treatment and maintaining this level, without requiring additional headache medication, for 7 days following discharge from the Emergency Department. Participants will be asked by phone how number of days they experienced headaches during the week after discharge from the emergency department. Reported values are participants who experienced no headaches at all during the 7 days immediately following discharge. |
| Secondary | Medication Preference as Assessed by Self-report | 7 days after discharge from emergency department | Participants will be asked, by phone, if they would want the same medication during a subsequent visit to the emergency department. Reported values indicate participants who responded "yes". |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Headache Days as Self-reported by Participants | 7 days after discharge from emergency department | days | MEAN | |
| SECONDARY | Number of Participants With Sustained Headache Freedom | 7 days after discharge from emergency department | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Medication Preference as Assessed by Self-report | 7 days after discharge from emergency department | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group6
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Headache Days as Self-reported by Participants | Control | 3.0 | 95% Confidence Interval 2.5 to 3.5 | days | |
| Headache Days as Self-reported by Participants | Experimental | 3.3 | 95% Confidence Interval 2.8 to 3.9 | days | |
| Number of Participants With Sustained Headache Freedom | Control | 10 | Participants | ||
| Number of Participants With Sustained Headache Freedom | Experimental | 6 | Participants | ||
| Medication Preference as Assessed by Self-report | Control | 76 | Participants | ||
| Medication Preference as Assessed by Self-report | Experimental | 75 | Participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Control | 109 | |
| Overall Study | STARTED | Experimental | 111 | |
| Overall Study | COMPLETED | Control | 101 | |
| Overall Study | COMPLETED | Experimental | 106 | |
| Overall Study | NOT COMPLETED | Control | 8 | |
| Overall Study | NOT COMPLETED | Experimental | 5 |
Source ClinicalTrials.gov
Adverse events4
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Akathisia | Nervous system disorders | Control | 2 | 109 | 2 |
| other | Akathisia | Nervous system disorders | Experimental | 7 | 111 | 7 |
| other | Injection site reaction | Skin and subcutaneous tissue disorders | Control | 1 | 109 | 1 |
| other | Injection site reaction | Skin and subcutaneous tissue disorders | Experimental | 9 | 111 | 9 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Control | 0 | 109 |
| Total, all-cause mortality | Experimental | 0 | 111 |
| Total, other adverse events | Control | 3 | 109 |
| Total, other adverse events | Experimental | 16 | 111 |
| Total, serious adverse events | Control | 0 | 109 |
| Total, serious adverse events | Experimental | 0 | 111 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 30449536 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons4
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Experimental vs Control: Number of Participants With Sustained Headache Freedom | Trial comparisons |
| Experimental vs Control: Medication Preference as Assessed by Self-report | Trial comparisons |
| Experimental vs Control: deaths from any cause | Trial comparisons |
| Experimental vs Control: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02847494
GET https://conductscience.org/api/trials/v1/NCT02847494/registered