Trial · NCT02850601
Dexamethasone Solution for the Treatment of Oral Lichen Planus
NCT02850601, Phase 2, Completed, Brigham and Women's Hospital; results first posted 2021-05-14
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Dexamethasone Solution for the Treatment of Oral Lichen Planus. Trials, record NCT02850601. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02850601
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Dexamethasone Solution for the Treatment of Oral Lichen Planus
- NCT number
- NCT02850601
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 24 participants, actual
- Lead sponsor
- Brigham and Women's Hospital
- Conditions
- Lichen Planus
- Interventions
- Dexamethasone
- First posted
- 2016-08-01
- Last updated
- 2021-06-14
- Results first posted
- 2021-05-14
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Oral Sensitivity | 4 weeks after the start of the trial | Subjects scored their worse sensitivity while eating over the past week. This score is substracted from their initial reported sensitivity at baseline. Reduction in oral symptoms of the worst sensitivity experienced in the past week on an 11 point scale (visual analogue scale 0-10). O signifies no sensitivity; 10 maximum sensitivity substracted from the same score collected at baseline before the treatment was initiated. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change in Oral Sensitivity | 4 weeks after the start of the trial | score on a scale | MEDIAN |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change in Oral Sensitivity | Dexamethasone Rinses | -4.5 | Standard Error 2.5 | score on a scale | |
| Change in Oral Sensitivity | Dexamethasone in Mucolox Rinses | -6.0 | Standard Error 1.5 | score on a scale |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Dexamethasone Solution | 12 | |
| Overall Study | STARTED | Dexamethasone Solution in Mucolox™ | 12 | |
| Overall Study | COMPLETED | Dexamethasone Solution | 12 | |
| Overall Study | COMPLETED | Dexamethasone Solution in Mucolox™ | 12 | |
| Overall Study | NOT COMPLETED | Dexamethasone Solution | 0 | |
| Overall Study | NOT COMPLETED | Dexamethasone Solution in Mucolox™ | 0 |
Source ClinicalTrials.gov
Adverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | constipation; abdomional discomfort | Gastrointestinal disorders | Dexamethasone Solution | 1 | 12 | 1 |
| serious | constipation; abdomional discomfort | Gastrointestinal disorders | Dexamethasone Solution in Mucolox™ | 0 | 12 | 0 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Dexamethasone Solution | 0 | 12 |
| Total, all-cause mortality | Dexamethasone Solution in Mucolox™ | 0 | 12 |
| Total, other adverse events | Dexamethasone Solution | 0 | 12 |
| Total, other adverse events | Dexamethasone Solution in Mucolox™ | 0 | 12 |
| Total, serious adverse events | Dexamethasone Solution | 1 | 12 |
| Total, serious adverse events | Dexamethasone Solution in Mucolox™ | 0 | 12 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Dexamethasone Solution vs Dexamethasone Solution in Mucolox™: deaths from any cause | Trial comparisons |
| Dexamethasone Solution vs Dexamethasone Solution in Mucolox™: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02850601
GET https://conductscience.org/api/trials/v1/NCT02850601/registered