Trial · NCT02860494
Topical Everolimus in Patients With Tuberous Sclerosis Complex
NCT02860494, Phase 2, Phase 3, Withdrawn, Hospices Civils de Lyon
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Topical Everolimus in Patients With Tuberous Sclerosis Complex. Trials, record NCT02860494. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02860494
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Topical Everolimus in Patients With Tuberous Sclerosis Complex
- NCT number
- NCT02860494
- Status
- Withdrawn
- Phases
- Phase 2, Phase 3
- Enrollment
- 0 participants, actual
- Lead sponsor
- Hospices Civils de Lyon
- Conditions
- Facial Angiofibromas
- Interventions
- Everolimus, Placebo
- First posted
- 2016-08-09
- Last updated
- 2021-05-03
- Other registries' IDs
- eudract:2018-002531-18
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Facial Angiofibroma Severity Index (FASI) | 6 months | The FASI is a composite score summing the scores for erythema (0-3), size (0-3) and extension of FA (2:\<50% of the cheek surface; 3:\>50% of the cheek surface). The FASI will be centrally-measured on patient's face photographs by an independent and blinded adjudication committee of 2 dermatologists, with third-dermatologist review for disagreements. |
| Secondary | FA size | 6 months | FA size (in millimetres) of the 3 largest targeted FA papules previously identified by the investigator |
| Secondary | Dermatologist's global assessment of efficacy | 6 months | using 7-point Likert scale |
| Secondary | Patient or parents self-assessment | 6 months | using 7-point Likert scale |
| Secondary | Local tolerance of the topically applied formulation using patient self-assessment | 6 months | |
| Secondary | blood levels of topically applied everolimus | 6 months | |
| Secondary | dryness score | 6 months | assessed by physicians |
| Secondary | scaling scores | 6 months | assessed by physicians |
| Secondary | Dermatological quality of life | 6 months | using DLQI (Dermatology Life Quality Index) for adults, CDLQI (Children's Dermatology Life Quality Index) for children |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02860494
GET https://conductscience.org/api/trials/v1/NCT02860494/registered