Trial · NCT02896400

Optimizing Tobacco Dependence Treatment in the Emergency Department

NCT02896400, Phase 3, Completed, Yale University; results first posted 2020-11-16

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Optimizing Tobacco Dependence Treatment in the Emergency Department. Trials, record NCT02896400. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02896400

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Optimizing Tobacco Dependence Treatment in the Emergency Department
NCT number: NCT02896400
Status: Completed
Phases: Phase 3
Enrollment: 1,056 participants, actual
Lead sponsor: Yale University
Conditions: Tobacco Use Disorder
Interventions: Brief Negotiated Interview (BNI), Nicotine replacement therapy (NRT), CT Smokers Quitline (QL), SmokefreeText (Text)
First posted: 2016-09-12
Last updated: 2020-12-04
Results first posted: 2020-11-16

Source ClinicalTrials.gov

Registered outcomes1

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Tobacco Abstinence	3 months	Abstinence self reported and verified by exhaled carbon monoxide

Source ClinicalTrials.gov

Outcomes1

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Tobacco Abstinence	3 months	All participants eligible for 3 month follow-up (deceased participants excluded). Each intervention group was compared with all participants who did not receive that intervention. The comparison group therefore differed for each intervention: BNI=526; NRT=525; QL=527; Text = 526.	Participants	COUNT_OF_PARTICIPANTS

Source ClinicalTrials.gov

Results by group8

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Value	Units
Tobacco Abstinence	Brief Negotiated Interview (BNI)	71	Participants
Tobacco Abstinence	Brief Negotiated Interview (BNI) CONTROL	49	Participants
Tobacco Abstinence	Nicotine Replacement Therapy (NRT)	76	Participants
Tobacco Abstinence	Nicotine Replacement Therapy (NRT) CONTROL	44	Participants
Tobacco Abstinence	Quitline (QL)	66	Participants
Tobacco Abstinence	Quitline (QL) CONTROL	54	Participants
Tobacco Abstinence	Text	61	Participants
Tobacco Abstinence	Text CONTROL	59	Participants

Source ClinicalTrials.gov

Participant flow192

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Baseline	STARTED	NRT+QL+Text	66
Baseline	STARTED	BNI+QL+Text	66
Baseline	STARTED	BNI+NRT+QL+Text	66
Baseline	STARTED	NRT+QL	66
Baseline	STARTED	BNI+QL	66
Baseline	STARTED	NRT Only	66
Baseline	STARTED	BNI+Text	66
Baseline	STARTED	BNI+NRT+Text	66
Baseline	STARTED	NRT+Text	66
Baseline	STARTED	BNI+NRT	66

1 to 10 of 192Source ClinicalTrials.gov

See all 192 participant flow

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals48

The totals the trial posted for each group.

Total	Group	At risk
Total, all-cause mortality	NRT+QL+Text	66
Total, all-cause mortality	BNI+QL+Text	66
Total, all-cause mortality	BNI+NRT+QL+Text	66
Total, all-cause mortality	NRT+QL	66
Total, all-cause mortality	BNI+QL	66
Total, all-cause mortality	NRT Only	66
Total, all-cause mortality	BNI+Text	66
Total, all-cause mortality	BNI+NRT+Text	66
Total, all-cause mortality	NRT+Text	66
Total, all-cause mortality	BNI+NRT	66

1 to 10 of 48Source ClinicalTrials.gov

See all 48 adverse event totals

Papers1

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as
29287665	DERIVED

Source PubMed

Grants1

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

Project	Title	Principal investigators	Organization	Funder	Fiscal years
R01CA201873	Optimizing Tobacco Dependence Treatment in the Emergency Department	DZIURA, JAMES DAVID	YALE UNIVERSITY	NATIONAL CANCER INSTITUTE	2016 to 2019

Source NIH RePORTER

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT02896400

GET https://conductscience.org/api/trials/v1/NCT02896400/flow?page=2

API reference For AI assistants