Trial · NCT02919917
Treatment of Post-SCI Hypotension
NCT02919917, Phase 2, Phase 3, Completed, James J. Peters Veterans Affairs Medical Center; results first posted 2025-02-21
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Treatment of Post-SCI Hypotension. Trials, record NCT02919917. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02919917
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Treatment of Post-SCI Hypotension
- NCT number
- NCT02919917
- Status
- Completed
- Phases
- Phase 2, Phase 3
- Enrollment
- 66 participants, actual
- Lead sponsor
- James J. Peters Veterans Affairs Medical Center
- Conditions
Spinal Cord Injury, Autonomic Dysreflexia, Orthostatic Hypotension, Baroreceptor Integrity, Sympathetic Integrity, Vagal Integrity, Hypotension, Cerebral Blood Flow, Blood Pressure, Venous Occlusion Plethysmography
- Interventions
- Midodrine Hydrochloride, Midodrine Hydrochloride
- First posted
- 2016-09-30
- Last updated
- 2025-02-21
- Results first posted
- 2025-02-21
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Affected Therapy Sessions | Inpatient hospitalization (up to 4 months) | Responses to the questions "was the therapy session affected by low BP or concern for low BP development?" between the usual care and BP threshold treatment groups. The percent of sessions with a "yes" response are reported. |
| Primary | Systolic Blood Pressure | Inpatient hospitalization (up to 4 months) | Systolic hypertension (\>/= 140 mmHg) |
| Secondary | Systolic Blood Pressure | Inpatient Hospitalizations (up to 4 months) | Systolic hypotension (males: \< 110 mmHg; females: \< 100 mmHg) |
| Secondary | Missed Therapy Sessions | Inpatient Hospitalizations (up to 4 months) | Percentages of missed therapy sessions, due to low BP or concern for low BP development, in the usual care and BP treatment groups |
Source ClinicalTrials.gov
Outcomes4
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Affected Therapy Sessions | Inpatient hospitalization (up to 4 months) | percentage of sessions | NUMBER | |
| PRIMARY | Systolic Blood Pressure | Inpatient hospitalization (up to 4 months) | percentage of BP assessments | NUMBER | |
| SECONDARY | Systolic Blood Pressure | Inpatient Hospitalizations (up to 4 months) | percentage of BP assessments | NUMBER | |
| SECONDARY | Missed Therapy Sessions | Inpatient Hospitalizations (up to 4 months) | percentage of missed therapy sessions | NUMBER |
Source ClinicalTrials.gov
Results by group8
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Affected Therapy Sessions | Usual Care Group | 16.4 | percentage of sessions | ||
| Affected Therapy Sessions | BP Threshold Treatment Group | 10.9 | percentage of sessions | ||
| Systolic Blood Pressure | Usual Care Group | 4.8 | percentage of BP assessments | ||
| Systolic Blood Pressure | BP Threshold Treatment Group | 5.3 | percentage of BP assessments | ||
| Systolic Blood Pressure | Usual Care Group | 39.7 | percentage of BP assessments | ||
| Systolic Blood Pressure | BP Threshold Treatment Group | 43.0 | percentage of BP assessments | ||
| Missed Therapy Sessions | Usual Care Group | 58.60 | percentage of missed therapy sessions | ||
| Missed Therapy Sessions | BP Threshold Treatment Group | 65.8 | percentage of missed therapy sessions |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Usual Care Group | 33 | |
| Overall Study | STARTED | BP Threshold Treatment Group | 33 | |
| Overall Study | COMPLETED | Usual Care Group | 29 | |
| Overall Study | COMPLETED | BP Threshold Treatment Group | 25 | |
| Overall Study | NOT COMPLETED | Usual Care Group | 4 | |
| Overall Study | NOT COMPLETED | BP Threshold Treatment Group | 8 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Usual Care Group | 0 | 29 |
| Total, all-cause mortality | BP Threshold Treatment Group | 0 | 25 |
| Total, other adverse events | Usual Care Group | 0 | 29 |
| Total, other adverse events | BP Threshold Treatment Group | 0 | 25 |
| Total, serious adverse events | Usual Care Group | 0 | 29 |
| Total, serious adverse events | BP Threshold Treatment Group | 0 | 25 |
Source ClinicalTrials.gov
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| BP Threshold Treatment Group vs Usual Care Group: deaths from any cause | Trial comparisons |
| BP Threshold Treatment Group vs Usual Care Group: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02919917
GET https://conductscience.org/api/trials/v1/NCT02919917/registered