Trial · NCT02929589
Ibuprofen to Decrease Opioid Use and Post-operative Pain Following Unilateral Inguinal Herniorrhaphy
NCT02929589, Phase 3, Terminated, Mike O'Callaghan Military Hospital; results first posted 2024-03-26
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Ibuprofen to Decrease Opioid Use and Post-operative Pain Following Unilateral Inguinal Herniorrhaphy. Trials, record NCT02929589. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02929589
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Ibuprofen to Decrease Opioid Use and Post-operative Pain Following Unilateral Inguinal Herniorrhaphy
- NCT number
- NCT02929589
- Status
- Terminated
- Phases
- Phase 3
- Enrollment
- 18 participants, actual
- Lead sponsor
- Mike O'Callaghan Military Hospital
- Conditions
- Pain, Hernia
- Interventions
- Ibuprofen, Opioid Medication, Placebo, Ibuprofen + Opioid medication
- First posted
- 2016-10-11
- Last updated
- 2024-03-26
- Results first posted
- 2024-03-26
- Limitations and caveats
- This study was terminated early as the advent of the use of robotic surgery made this study obsolete.
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Total Milligram Morphine Equivalent (MME) Units | 60 days post-operation | The primary outcome measure was milligram morphine equivalent units to measure pain intensity difference and total pain relief. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Total Milligram Morphine Equivalent (MME) Units | 60 days post-operation | No populations were analyzed as study was terminated as obsolete after the development and use of robotic arms during surgery. Any data collected was not analyzed by a biostatistician. Raw data are reported for 15 subjects. 3/15 were screenfails in Group A. | milligram morphine equivalence units | MEAN |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Total Milligram Morphine Equivalent (MME) Units | Opioid naïve Patients-Group A | 72 | Full Range 0 to 207 | milligram morphine equivalence units | |
| Total Milligram Morphine Equivalent (MME) Units | Opioid naïve Patients-Group B | 88 | Full Range 0 to 340 | milligram morphine equivalence units |
Source ClinicalTrials.gov
Participant flow12
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Opioid naïve Patients-Group A | 11 | |
| Overall Study | STARTED | Non-Opioid naïve Patients-Group C | 0 | |
| Overall Study | STARTED | Opioid naïve Patients-Group B | 7 | |
| Overall Study | STARTED | Non-Opioid naïve Patients-Group D | 0 | |
| Overall Study | COMPLETED | Opioid naïve Patients-Group A | 8 | |
| Overall Study | COMPLETED | Non-Opioid naïve Patients-Group C | 0 | |
| Overall Study | COMPLETED | Opioid naïve Patients-Group B | 7 | |
| Overall Study | COMPLETED | Non-Opioid naïve Patients-Group D | 0 | |
| Overall Study | NOT COMPLETED | Opioid naïve Patients-Group A | 3 | |
| Overall Study | NOT COMPLETED | Non-Opioid naïve Patients-Group C | 0 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 participant flowAdverse events4
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Adverse Event | Gastrointestinal disorders | Opioid naïve Patients-Group A | 1 | 11 | 1 |
| other | Adverse Event | Gastrointestinal disorders | Non-Opioid naïve Patients-Group C | 0 | 0 | 0 |
| other | Adverse Event | Gastrointestinal disorders | Opioid naïve Patients-Group B | 0 | 7 | 0 |
| other | Adverse Event | Gastrointestinal disorders | Non-Opioid naïve Patients-Group D | 0 | 0 | 0 |
Source ClinicalTrials.gov
Adverse event totals12
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Opioid naïve Patients-Group A | 0 | 11 |
| Total, all-cause mortality | Non-Opioid naïve Patients-Group C | 0 | 0 |
| Total, all-cause mortality | Opioid naïve Patients-Group B | 0 | 7 |
| Total, all-cause mortality | Non-Opioid naïve Patients-Group D | 0 | 0 |
| Total, other adverse events | Opioid naïve Patients-Group A | 1 | 11 |
| Total, other adverse events | Non-Opioid naïve Patients-Group C | 0 | 0 |
| Total, other adverse events | Opioid naïve Patients-Group B | 0 | 7 |
| Total, other adverse events | Non-Opioid naïve Patients-Group D | 0 | 0 |
| Total, serious adverse events | Opioid naïve Patients-Group A | 0 | 11 |
| Total, serious adverse events | Non-Opioid naïve Patients-Group C | 0 | 0 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 adverse event totalsPapers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02929589
GET https://conductscience.org/api/trials/v1/NCT02929589/registered