Effects of Caffeine on EEG Theta/Beta Ratio and Cognitive Control
NCT02940808, Not applicable, Completed, Leiden University Medical Center
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Effects of Caffeine on EEG Theta/Beta Ratio and Cognitive Control | ClinicalTrials.gov |
| NCT number | NCT02940808 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 41 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Leiden University Medical Center | ClinicalTrials.gov |
| Conditions | Caffeine | ClinicalTrials.gov |
| Interventions | Caffeine (200mg), Placebo | ClinicalTrials.gov |
| First posted | 2016-10-21 | ClinicalTrials.gov |
| Last updated | 2017-03-08 | ClinicalTrials.gov |
Registered outcomes 13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Attentional focus (RT) | Approx. 45 min after capsule consumption | TACT focus RTs on incongruent v congruent (correct) trials. | ClinicalTrials.gov |
| Primary | Attentional shift (RT) | Approx. 45 min after capsule consumption | TACT shift RTs on post-shift trials compared to pre-shift (correct) trials. | ClinicalTrials.gov |
| Primary | Emotional interference (RT) | Approx. 70 min after capsule consumption | Emotional Stroop Task RTs for neutral, positive, and negative (correct) trials. | ClinicalTrials.gov |
| Primary | EEG theta/beta ratio | Approx. 30 min after capsule consumption | For mediation analyses, change in EEG theta/beta ratio after caffeine consumption relative to placebo consumption. | ClinicalTrials.gov |
| Primary | EEG theta/beta ratio | Baseline | For moderation analyses, baseline-measured spontaneous EEG theta/beta ratio. | ClinicalTrials.gov |
| Primary | Spontaneous eye-blink rates | Baseline | For moderation analyses, baseline-measured spontaneous eye-blink rates. | ClinicalTrials.gov |
| Primary | Trait anxiety | Baseline | Self-reported trait anxiety (STAI-t) | ClinicalTrials.gov |
| Primary | Working memory (ACC) | Approx. 60 min after capsule consumption | N-Back accuracy (% correct) in the 1-back and 3-back conditions. | ClinicalTrials.gov |
| Primary | Working memory (RT) | Approx. 60 min after capsule consumption | N-Back RTs on correct trials in the 1-back and 3-back conditions. | ClinicalTrials.gov |
| Secondary | Attentional focus (ACC) | Approx. 45 min after capsule consumption | TACT focus accuracy on incongruent v congruent trials. | ClinicalTrials.gov |
| Secondary | Attentional shift (ACC) | Approx. 45 min after capsule consumption | TACT shift accuracy on post-shift trials compared to pre-shift trials. | ClinicalTrials.gov |
| Other | TBR and ACS | Baseline | Relation between TBR and ACS. | ClinicalTrials.gov |
| Other | TBR and STAI-t | Baseline | Relation between TBR and STAI-t. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 14
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 6187540 | BACKGROUND | PubMed |
| 6640274 | BACKGROUND | PubMed |
| 10945922 | BACKGROUND | PubMed |
| 12003445 | BACKGROUND | PubMed |
| 12559224 | BACKGROUND | PubMed |
| 15997602 | BACKGROUND | PubMed |
| 17516812 | BACKGROUND | PubMed |
| 19455173 | BACKGROUND | PubMed |
| 19897008 | BACKGROUND | PubMed |
| 20816912 | BACKGROUND | PubMed |
| 21531388 | BACKGROUND | PubMed |
| 23241646 | BACKGROUND | PubMed |
| 24379166 | BACKGROUND | PubMed |
| 27555290 | BACKGROUND | PubMed |
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 3
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| 1-Back Task | Primary outcome | ConductCognition |
| Emotional Stroop Task | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)